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AssigneeTelormedix SA
InventorsLorenzo Leoni, Roberto Maj, Franco Pattarino, Carlo Vecchio
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The present invention relates in general to the field of modulators of the innate immune system, particularly to pharmaceutical compositions comprising imidazoquinolin(amines) and derivatives thereof, preferably suitable for local administration, such as, intravesical administration. In addition, the present invention concerns the use of imidazoquinolin(amines) and derivatives thereof for intravesical treatment of bladder diseases, such as, for example, bladder cancer and cystitis. The present invention furthermore comprises methods of treatment for these diseases as well as methods of administration of the inventive pharmaceutical compositions.
A pharmaceutical composition comprising imiquimod, lactic acid, a polymer and cyclodextrin, wherein the polymer consists of Poloxamer 407 in an amount of 11% (w/v) to 18% (w/v), and the composition is for bladder instillation.
A pharmaceutical composition comprising imiquimod in an amount of about 0.1% (w/v) to about 1% (w/v), lactic acid in a concentration of about 0.075 M to about 0.125 M, cyclodextrin in an amount of about 2% (w/v) to about 6% (w/v), and a polymer consisting of Poloxamer 407 in an amount of 11% (w/v) to 18% (w/v), and the composition is aqueous and is for bladder instillation.
Dependencies are inferred from the claim text.