Carbohydrate binding molecules
AssigneeUniversity Court of the University of St Andrews
InventorsHelen Connaris, Garry Taylor
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Abstract
The present invention provides compounds, compositions, medicaments and methods comprising or using carbohydrate binding molecules. More specifically, the invention provides a means of treating diseases and/or conditions caused or contributed to by pathogens, particularly microbial pathogens and methods of screening, identifying, detecting tagging and/or labelling carbohydrates.
Claims44
A method of treating or preventing a disease caused or contributed to by a pathogen, said method comprising the step of administering a therapeutically effective amount of a carbohydrate binding module (CBM) to a subject in need thereof, wherein the CBM comprises one or more isolated family 40 CBMs (CBM40).
A method of treating or preventing disease caused or contributed to by a pathogen, said method comprising the step of administering a therapeutically effective amount of a carbohydrate binding module (CBM) to a subject in need thereof, wherein the CBM is a CBM polymer comprising two or more CBM40 monomers.
A method of treating or preventing a disease caused or contributed to by a pathogen, said method comprising administering a pharmaceutical composition comprising a therapeutically effective amount of a carbohydrate binding module (CBM) and a pharmaceutically acceptable excipient to a subject in need thereof, wherein the CBM comprises one or more isolated family 40 CBMs (CBM40).
A method of treating or preventing a disease caused or contributed to by a pathogen, said method comprising administering a pharmaceutical composition comprising a therapeutically effective amount of a carbohydrate binding module (CBM) and a pharmaceutically acceptable excipient to a subject in need thereof, wherein the CBM is a multivalent CBM comprising two or more CBM40 monomers.
Dependencies are inferred from the claim text.