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US 9,066,858 B2Granted
Pharmaceutical composition for the sublingual administration of progesterone, and method for its preparation
AssigneeAltergon S.A.
InventorsLorenzo Bellorini, Luca Nocelli, Giorgio Zoppetti
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Abstract
A pharmaceutical composition is described for the sublingual administration of progesterone in the form of a rapidly-disintegrating tablet, which is capable of promoting a greater bioavailability of the progesterone; a method for preparing said pharmaceutical composition is also described.
Claims1
A pharmaceutical composition for the sublingual administration of progesterone complexed with a cyclodextrin, in the form of a rapidly-disintegrating tablet having the following composition by weight:
- Progesterone complex
- with hydroxypropyl-β-cyclodextrin:
- 33.1%
- Polyvinylpyrrolidone CL:
- 5.6%
- Citric acid anhydrous powder:
- 9.8%
- Sodium bicarbonate powder:
- 12.0%
- Calcium silicate:
- 13.5%
- Sorbitol:
- 17.3%
- Sodium stearyl fumarate:
- 0.8%
- Aspartame:
- 3.0%
- Flavouring:
- 5.0%.
16 more elements
Dependencies are inferred from the claim text.