Prosthetic heart valve formation
AssigneeBoston Scientific Scimed, Inc.
InventorsPeter Edelman, Horng-Ban Lin, Scott Fisher, Jeffrey S. Lindquist, Huisun Wang, Richard C. Gunderson
Life of this patent
Estimating the term…
Abstract
A prosthetic heart valve includes a base and a plurality of polymeric leaflets. Each leaflet has a root portion coupled to the base, and each leaflet has an edge portion substantially opposite the root portion and movable relative to the root portion to coapt with a respective edge portion of at least one of the other leaflets of the plurality of leaflets. Each leaflet includes) at least two polymers along at least one portion of the leaflet, and each leaflet has a composition gradient of each of the at least two polymers along at least one portion of the leaflet.
Claims17
A prosthetic heart valve comprising:
- a base;
- a plurality of polymeric leaflets, each leaflet having a root portion coupled to the base, each leaflet having an edge portion opposite the root portion and movable relative to the root portion to coapt with a respective edge portion of at least one of the other leaflets of the plurality of leaflets, each leaflet comprising at least two polymers, and each leaflet having a composition gradient of each of the at least two polymers along at least one portion of the leaflet, wherein each of the at least two polymers has respective hard segments and soft segments and the ratio of hard segments to soft segments in one of the at least two polymers is higher than the ratio of hard segments to soft segments in another of the at least two polymers, wherein each of the at least two polymers is a respective block polymer, wherein the soft segments of each block polymer is a copolymer of a first monomer and a second monomer and the comonomer ratio of the first monomer to the second monomer is varied in combination with the hard segment to soft segment ratio, wherein the first monomer is dimethyl siloxane and the second monomer is hexamethylene carbonate.
A prosthetic heart valve comprising:
- a base;
- a plurality of polymeric leaflets, each leaflet having a root portion coupled to the base, each leaflet having an edge portion opposite the root portion and movable relative to the root portion to coapt with a respective edge portion of at least one of the other leaflets of the plurality of leaflets, each leaflet comprising at least two polymers, and each leaflet having a composition gradient of each of the at least two polymers along at least one portion of the leaflet, wherein one of the at least two polymers is a surface coating disposed over at least a portion of another of the at least two polymers, along at least one side of the leaflet extending from the root portion to the edge portion, wherein each of the at least two polymers have respective hard and soft segments, the hard and soft segments of the surface coating having the same molecular structure as the respective hard and soft segments of the other of the at least two polymers, and the surface coating comprising surface active end groups, wherein the surface active end groups comprise non-polar surface active end groups.
Dependencies are inferred from the claim text.