# US 9,046,338 B2 · Full-field optical coherence tomography system for imaging an object > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 9,046,338 B2 - Document ID: US9046338B2 - Status: Granted - Kind: B2 - Application number: 13/846,378 - Filed: 2013-03-18 - Published: 2013-09-12 - Granted: 2015-06-02 - Earliest claimed: 2010-09-17 - Assignees: Lltech Management - Applicants: Lltech Management - Inventors: Albert Boccara; Anne Latrive; Bertrand Le Conte De Poly; Fabrice Harms - Web page: https://patentgrep.com/patent/US9046338B2 ## CPC - G01B 9/02091: Tomographic interferometers, e.g. based on optical coherence - A61B 5/0066: {Optical coherence imaging} - A61B 5/0084: {for introduction into the body, e.g. by catheters (A61B5/1459 takes precedence)} - G01N 21/4795: {spatially resolved investigating of object in scattering medium (in vivo A61B)} - G01B: MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) - G01N: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES (measuring or testing apparatus or processes other than immunoassay, involving enzymes or microorganisms C12M, C12Q) ## Abstract The present invention relates to a full-field optical coherence tomography system (300) for imaging an object (319), comprising a light source (301), a first interferometric device having means for splitting an input light beam and comprising at least a reflecting surface (307), a second interferometric device having means for splitting the spectrally modulated output beam and comprising at least a reflecting surface, a multichannel acquisition device (321), the system (300) being characterized in that at least one of the interferometric devices includes at least a focusing optical element arranged to focus at least one of the input beams or at least one of the output beams onto the corresponding reflecting surface of the corresponding interferometric device. ## Claims ### Claim 1 A full-field optical coherence tomography system for imaging an object, comprising: a light source generating an input light beam having a low temporal coherence; a processing interferometric device comprising: means for splitting the input light beam into a first input beam and a second input beam, the first input beam and the second input beam being recombined into a spectrally modulated output beam; and at least one reflecting surface of the processing interferometric device arranged to reflect the first input beam or the second input beam; an imaging interferometric device comprising: means for splitting the spectrally modulated output beam into a first output beam and a second output beam; and at least one reflecting surface of the imaging interferometric device arranged to reflect the first output beam or the second output beam; and a multichannel acquisition device arranged to receive a recombination of the first output beam and the second output beam, wherein the processing interferometric device includes at least one focusing optical element arranged between the means for splitting the input light beam and the at least one reflecting surface of the processing interferometric device, the at least one focusing optical element configured to focus at least one of the input beams onto the corresponding reflecting surface of the processing interferometric device, wherein the at least one focusing optical element comprises at least one first lens, and a material of said first lens of the processing interferometric device induces an optical path length difference between the first and the second input beams of the processing interferometric device, said optical path length difference being compensated by a second lens, and wherein the full-field optical coherence tomography system further comprises a probe coupled to the imaging interferometric device, said probe having a distal end to be placed in a proximity of the object and said second lens being placed at said distal end. ### Claim 2 (depends on 1) The full-field optical coherence tomography system according to claim 1, wherein the processing interferometric device has a first arm and a second arm respectively comprising a first reflecting surface and a second reflecting surface respectively arranged to reflect the first input beam and the second input beam, and wherein the at least one focusing optical element in said first arm or in said second arm respectively is arranged to focus the first input beam onto said first reflecting surface or the second input beam onto said second reflecting surface. ### Claim 3 (depends on 1) The full-field optical coherence tomography system according to claim 1, wherein the imaging interferometric device has a first arm and a second arm respectively comprising a first reflecting surface and a second reflecting surface respectively arranged to reflect the first output beam and the second output beam. ### Claim 4 (depends on 1) The full-field optical coherence tomography system according to claim 1, wherein said path length difference is substantially equal to an optical path length difference between the first beam and second beam of the imaging interferometric device. ### Claim 5 (depends on 1) The full-field optical coherence tomography system according to claim 1, wherein the at least one focusing optical element comprises objective optics so that the processing interferometric device forms a Linnik interferometer. ### Claim 6 (depends on 1) The full-field optical coherence tomography system according to claim 1, wherein said at least one first lens of the processing interferometric device and said second lens of the imaging interferometric device have same optical characteristics. ### Claim 7 (depends on 6) The full-field optical coherence tomography system according to claim 6, further comprising said probe is a miniaturized probe. ### Claim 8 (depends on 7) The full-field optical coherence tomography system according to claim 7, wherein the processing interferometric device or the imaging interferometric device presents a common optical path within the probe. ### Claim 9 (depends on 7) The full-field optical coherence tomography system according to claim 7, wherein the miniaturized probe comprises a fiber bundle having a diameter between about 0.2 mm and about 10 mm. ### Claim 10 (depends on 1) The full-field optical coherence tomography system according to claim 1, wherein at least two first lenses of the processing interfermetric device are arranged to form an optical cavity, and at least two second lenses of the imaging interferometric device are arranged to form an optical cavity. ### Claim 11 (depends on 1) The full-field optical coherence tomography system according to claim 1, wherein said probe's distal end is oriented toward the object. ### Claim 12 (depends on 11) The full-field optical coherence tomography system according to claim 11, wherein the probe is a miniaturized probe comprising a plurality of optical lenses, each optical lens having a diameter between about 0.5 mm and about 5 mm. ### Claim 13 (depends on 1) The full-field optical coherence tomography system according to claim 1, wherein the optical path length difference is greater than or equal to about 1 mm. ### Claim 14 (depends on 1) The full-field optical coherence tomography system according to claim 1, wherein the full-field optical coherence tomography system comprises at least one polarizing optic arranged before the multichannel acquisition device. ### Claim 15 (depends on 1) The full-field optical coherence tomography system according to claim 1, further comprising at least one motorized component, the motorized component controlling the optical path length difference between the first input beam and the second input beam. ### Claim 16 (depends on 15) The full-field optical coherence tomography system according to claim 15, wherein the motorized component is arranged in the processing interferometric device or in the imaging interferometric device. ### Claim 17 (depends on 1) The full-field optical coherence tomography system according to claim 1, wherein said at least one first and second lenses are gradient index lens. ### Claim 18 A full-field optical coherence tomography system for imaging an object, comprising: a light source generating an input light beam having a low temporal coherence; an imaging interferometric device comprising: means for splitting the input light beam into a first input beam and a second input beam, the first input beam and the second input beam being recombined into a spectrally modulated output beam; and at least one reflecting surface of the imaging interferometric device arranged to reflect the first input beam or the second input beam; a processing interferometric device comprising: means for splitting the spectrally modulated output beam into a first output beam and a second output beam; at least one reflecting surface of the processing interferometric device arranged to reflect the first output beam or the second output beam; and a multichannel acquisition device arranged to receive a recombination of the first output beam and the second output beam, wherein the processing interferometric device includes at least one focusing optical element arranged between the means for splitting the output light beam and the at least one reflecting surface of the processing interferometric device, the at least one focusing optical element configured to focus at least one of the output beams onto the corresponding reflecting surface of the processing interferometric device, wherein the at least one focusing element comprises at least one first lens, and a material of said first lens of the processing interferometric device induces an optical path length difference between the first and the second output beams of the processing interferometric device, said optical path length difference being compensated by at least one second lens, and wherein the full-field optical coherence tomography system further comprises a probe coupled to the imaging interferometric device, said probe having a distal end to be placed in a proximity of the object and said at least one second lens being placed at said distal end. ### Claim 19 (depends on 18) The full-field optical coherence tomography system according to claim 18, wherein said at least one first and second lenses are gradient index lens. ### Claim 20 (depends on 18) The full-field optical coherence tomography system according to claim 18, further comprising at least one motorized component, the motorized component controlling the optical path length difference between the first and the second output beams.