# US 9,040,945 B1 · Method of mechanically controlling the amount of energy to reach a patient undergoing intraoperative electron radiation therapy > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 9,040,945 B1 - Document ID: US9040945B1 - Status: Granted - Kind: B1 - Application number: 14/206,938 - Filed: 2014-03-12 - Granted: 2015-05-26 - Earliest claimed: 2013-03-12 - Applicants: Precision Accelerators of Louisiana LLC - Inventors: Jonathan S. Hayman - Web page: https://patentgrep.com/patent/US9040945B1 ## CPC - A61N 5/1075: {for testing, calibrating, or quality assurance of the radiation treatment apparatus} - A61N 5/1015: {Treatment of resected cavities created by surgery, e.g. lumpectomy} - A61N 5/1083: {Robot arm beam systems} - A61N 2005/1089: {Electrons} - A61N 2005/1096: {Elements inserted into the radiation path placed on the patient, e.g. bags, bolus, compensators} - A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B) ## Abstract Apparatus for performing electron radiation therapy on a breast cancer patient preferably includes an intraoperative electron radiation therapy machine, an intraoperative electron radiation therapy collimator tube connected to the intraoperative electron radiation therapy machine, and a plurality of filters made of a material having substantially the same density as human breast tissue for placement between the machine and the patient to change the energy of a monoenergetic beam after the beam has left the machine, allowing a filter to be chosen to reduce the energy traveling through the tube to a desired amount of energy to treat the patient. A method of controlling the amount of energy to reach a breast cancer patient undergoing electron radiation therapy includes selecting a filter made of a material having substantially the same density as human tissue and placing the filter between an intraoperative electron radiation therapy machine and a breast cancer patient to change the energy of a monoenergetic beam after it has left the machine, the filter being chosen to reduce the energy traveling from the machine to a desired amount of energy to treat the patient. ## Claims ### Claim 1 A method of controlling the amount of energy to reach a breast cancer patient undergoing intraoperative electron radiation therapy, comprising: providing an intraoperative electron radiation therapy machine having a head for producing a monoenergetic beam; selecting a bolus made of a material having substantially the same density as human breast tissue and placing the bolus between the head of the machine and the patient to change the energy of a monoenergetic beam after the monoenergetic beam has left the part of the machine that accelerates the electrons to the desired energy, the bolus being chosen to reduce the energy traveling through the tube to a desired amount of energy to treat the patient. ### Claim 2 (depends on 1) The method of claim 1, wherein the bolus is integral with a collimator tube which attaches to the head of the intraoperative electron radiation therapy machine. ### Claim 3 (depends on 2) The method of claim 2, wherein the tube is made of poly(methyl methacrylate). ### Claim 4 (depends on 1) The method of claim 1, wherein the bolus comprises at least one material from the group consisting of isodense materials made up primarily or entirely of carbon, oxygen, and hydrogen, such as PMMA, Delrin brand acetal resin, UHMW (ultra-high molecular weight polyethylene), polyethylene, polypropylene, ABS, acrylic, Bakelite, CPVC, fiberglass, Kynar brand plastic, Lexan brand plastic, Micarta brand plastic, PVC, Ryton brand plastic, and Teflon brand polytetrafluoroethylene. ### Claim 5 (depends on 1) The method of claim 1, wherein the bolus comprises poly(methyl methacrylate). ### Claim 6 (depends on 1) The method of claim 1, further comprising calibrating the intraoperative electron radiation therapy machine after it is moved and before it is used to treat a patient. ### Claim 7 A method of controlling the amount of energy to reach a breast cancer patient undergoing intraoperative electron radiation therapy, comprising: providing an intraoperative electron radiation therapy machine having a head for producing a beam; controlling the intraoperative electron radiation therapy machine such that the head produces a monoenergetic beam during calibration of the machine and treatment of the patient; calibrating the intraoperative electron radiation therapy machine after it is moved and before it is used to treat a patient; selecting a bolus made of a material having substantially the same density as human breast tissue and placing the bolus between the head of the machine and the patient to change the energy of a monoenergetic beam after it has left the machine, the bolus being chosen to reduce the energy traveling through the tube to a desired amount of energy to treat the patient. ### Claim 8 (depends on 7) The method of claim 7, wherein the bolus is integral with a collimator tube which attaches to the head of the intraoperative electron radiation therapy machine. ### Claim 9 (depends on 8) The method of claim 8, wherein the tube is made of poly(methyl methacrylate). ### Claim 10 (depends on 7) The method of claim 7, wherein the bolus comprises at least one material from the group consisting of isodense materials made up primarily or entirely of carbon, oxygen, and hydrogen, such as poly(methyl methacrylate), Delrin brand acetal resin, UHMW (ultra-high molecular weight polyethylene), polyethylene, polypropylene, ABS, acrylic, Bakelite, CPVC, fiberglass, Kynar brand plastic, Lexan brand plastic, Micarta brand plastic, PVC, Ryton brand plastic, and Teflon brand polytetrafluoroethylene. ### Claim 11 (depends on 7) The method of claim 7, wherein the bolus comprises poly(methyl methacrylate). ### Claim 12 Apparatus for performing electron radiation therapy on a patient, the apparatus comprising: a plurality of boluses for use with an intraoperative electron radiation therapy machine having a head for producing an energy beam, the boluses made of a material having substantially the same density as human tissue for placement between the head of the machine and the patient to change the energy of a beam after it has left the machine, the bolus being chosen to reduce the energy traveling through the tube to a desired amount of energy to treat the patient. ### Claim 13 (depends on 12) The apparatus of claim 12, wherein the boluses comprise at least one material from the group consisting of isodense materials made up primarily or entirely of carbon, oxygen, and hydrogen, such as poly(methyl methacrylate), Delrin brand acetal resin, UHMW (ultra-high molecular weight polyethylene), polyethylene, polypropylene, ABS, acrylic, Bakelite, CPVC, fiberglass, Kynar brand plastic, Lexan brand plastic, Micarta brand plastic, PVC, Ryton brand plastic, and Teflon brand polytetrafluoroethylene. ### Claim 14 (depends on 12) The apparatus of claim 12, wherein the boluses comprise poly(methyl methacrylate). ### Claim 15 (depends on 12) The apparatus of claim 12, further comprising a collimator tube. ### Claim 16 (depends on 15) The apparatus of claim 15, wherein the tube is made of at least one material from the group consisting of isodense materials made up primarily or entirely of carbon, oxygen, and hydrogen, such as poly(methyl methacrylate), Delrin brand acetal resin, UHMW (ultra-high molecular weight polyethylene), polyethylene, polypropylene, ABS, acrylic, Bakelite, CPVC, fiberglass, Kynar brand plastic, Lexan brand plastic, Micarta brand plastic, PVC, Ryton brand plastic, and Teflon brand polytetrafluoroethylene. ### Claim 17 (depends on 15) The apparatus of claim 15, wherein the tube is made of poly(methyl methacrylate). ### Claim 18 (depends on 12) The apparatus of claim 12, wherein at least some of the boluses are integral with collimator tubes. ### Claim 19 (depends on 12) The apparatus of claim 12, further comprising the intraoperative electron radiation therapy machine. ### Claim 20 Apparatus for performing electron radiation therapy on a breast cancer patient, the apparatus comprising: an intraoperative electron radiation therapy machine having a head for producing a beam of energy; an intraoperative electron radiation therapy collimator tube connected to the intraoperative electron radiation therapy machine; a plurality of boluses made of a material having substantially the same density as human breast tissue to change the energy of a beam after the beam has left the head of the machine, allowing a bolus to be chosen to reduce the energy traveling from the head to a desired amount of energy to treat the patient. ### Claim 21 (depends on 20) The apparatus of claim 20, wherein the boluses comprise at least one material from the group consisting of isodense materials made up primarily or entirely of carbon, oxygen, and hydrogen, such as poly(methyl methacrylate), Delrin brand acetal resin, UHMW (ultra-high molecular weight polyethylene), polyethylene, polypropylene, ABS, acrylic, Bakelite, CPVC, fiberglass, Kynar brand plastic, Lexan brand plastic, Micarta brand plastic, PVC, Ryton brand plastic, and Teflon brand polytetrafluoroethylene. ### Claim 22 (depends on 20) The apparatus of claim 20, wherein the boluses comprise poly(methyl methacrylate). ### Claim 23 (depends on 20) The apparatus of claim 20, wherein the tube is made of at least one material from the group consisting of isodense materials made up primarily or entirely of carbon, oxygen, and hydrogen, such as poly(methyl methacrylate), Delrin brand acetal resin, UHMW (ultra-high molecular weight polyethylene), polyethylene, polypropylene, ABS, acrylic, Bakelite, CPVC, fiberglass, Kynar brand plastic, Lexan brand plastic, Micarta brand plastic, PVC, Ryton brand plastic, and Teflon brand polytetrafluoroethylene. ### Claim 24 (depends on 20) The apparatus of claim 20, wherein the tube is made of poly(methyl methacrylate). ### Claim 25 (depends on 20) The apparatus of claim 20, wherein at least some of the boluses are integral with collimator tubes. ### Claim 26 (depends on 20) The apparatus of claim 20, wherein the head produces a beam of a single energy. ### Claim 27 (depends on 7) The method of claim 7, wherein the intraoperative electron radiation therapy machine produces a beam of a single energy. ### Claim 28 (depends on 7) The method of claim 7, wherein the intraoperative electron radiation therapy machine produces a beam of about 10 MeV.