# US 9,040,580 B2 · Method for prevention or treatment of degenerative neurologial brain disorders

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- Number: US 9,040,580 B2
- Document ID: US9040580B2
- Status: Granted
- Kind: B2
- Application number: 13/820,520
- Filed: 2011-05-18
- Published: 2013-07-11
- Granted: 2015-05-26
- Earliest claimed: 2010-09-03
- Assignees: Braintropia Co., Ltd.
- Applicants: Yoo-Hun Suh; Sushruta Koppula; Su-Jin Noh
- Inventors: Yoo-Hun Suh; Sushruta Koppula; Su-Jin Noh
- Web page: https://patentgrep.com/patent/US9040580B2

## CPC

- A61K 31/235: having an aromatic ring attached to a carboxyl group
- A61P 25/00: Drugs for disorders of the nervous system
- A61P 25/14: for treating abnormal movements, e.g. chorea, dyskinesia
- A61P 25/16: Anti-Parkinson drugs
- A61P 25/28: for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

## Abstract

The present invention relates to a method for the prevention or treatment of degenerative neurological brain disorders and, more specifically, relates to a method for the prevention or treatment of degenerative neurological brain disorders, such as Parkinson's disease, Alzheimer's dementia (senile dementia), stroke, Lou Gehrig's disease, Pick's disease, Creutzfeldt-Jakob disease, Huntington's disease, progressive supranuclear palsy, spinocerebellar degeneration, cerebellar atrophy, multiple sclerosis, post-traumatic stress disorder, and amnesia. The method includes administering to a subject in need thereof a therapeutically effective amount of a composition, wherein the composition contains a paraben compound as an active ingredient having effects that are useful in combating oxidation to remove active oxygen, suppressing cell-death, improving impaired movement, and enhancing declining memory.

## Claims

### Claim 1

A method for treatment of Parkinson's disease, the method comprising administering to a subject in need thereof a therapeutically effective amount of at least one compound selected from the group consisting of methylparaben and ethylparaben.

### Claim 2 (depends on 1)

The method according to claim 1, wherein the compound is methylparaben.

### Claim 3 (depends on 1)

The method according to claim 1, wherein the compound is formulated into granulates, powders, syrups, solutions, suspensions, tablets, capsules, troches, pills, injections, or suppositories.