# US 9,040,285 B2 · Sensing device for sensing a fluid

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- Number: US 9,040,285 B2
- Document ID: US9040285B2
- Status: Granted
- Kind: B2
- Application number: 13/140,175
- Filed: 2009-12-07
- Published: 2011-12-08
- Granted: 2015-05-26
- Earliest claimed: 2008-12-18
- Assignees: Koninklijkle Philips N.V.
- Applicants: Albert Hendrik Jan Immink; Albert F. Gootzen; Dirk Jan Nelly Vananderoye; Petrus Johannes Wilhelmus Van Lankvelt
- Inventors: Albert Hendrik Jan Immink; Albert F. Gootzen; Dirk Jan Nelly Vananderoye; Petrus Johannes Wilhelmus Van Lankvelt
- Web page: https://patentgrep.com/patent/US9040285B2

## CPC

- G01N 33/54373: {involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings}
- G01N 21/03: Cuvette constructions
- G01N 21/11: Filling or emptying of cuvettes
- G01N 21/552: Attenuated total reflection
- B01L 2200/027: for microfluidic devices
- B01L 2200/04: Exchange or ejection of cartridges, containers or reservoirs
- B01L 2300/048: enabling gas exchange, e.g. vents
- B01L 2300/0627: Sensor or part of a sensor is integrated
- B01L 2300/0816: Cards, e.g. flat sample carriers usually with flow in two horizontal directions
- B01L 2300/087: Multiple sequential chambers
- B01L 2300/14: Means for pressure control
- B01L 2400/0481: squeezing of channels or chambers
- G01N 2021/0346: {Capillary cells; Microcells}
- G01N: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES (measuring or testing apparatus or processes other than immunoassay, involving enzymes or microorganisms C12M, C12Q)
- B01L: CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE

## Abstract

A sensing device including an inlet port for receiving a fluid, a measurement chamber for sensing the fluid, a fluid channel coupling the inlet port and the measurement chamber for transporting the fluid from the inlet port to the measurement chamber, and a fluid stop unit for stopping and controllably releasing the flow of fluid between the inlet port and the measurement chamber.

## Claims

### Claim 1

Sensing device for sensing a fluid, comprising:
an inlet port for receiving the fluid;
a measurement chamber for sensing the fluid;
a fluid channel coupling the inlet port and the measurement chamber for transporting fluid from the inlet port to the measurement chamber; and
a fluid stop unit for stopping and controllably releasing the flow of fluid between the inlet port and the measurement chamber, the fluid stop unit including
a fluidic stop element configured to stop the flow of fluid between the inlet port and the measurement chamber,
a venting hole arranged behind the measurement chamber with respect to a flow direction from the inlet port to the measurement chamber and coupled to the fluid channel, and
a pressure control unit configured to selectively increase a pressure in a first part of the fluid channel between the inlet port and the fluidic stop element to force the fluid past the fluidic stop element, the pressure control unit being arranged at a first section of the device and being slidable between an opened position and a closed position, wherein in the opened position the inlet port is uncovered by the pressure control unit and a first pressure is present in the first part of the fluid channel, wherein in the closed position the inlet port is sealed by the pressure control unit and a second pressure is produced in the first part of the fluid channel, and wherein the second pressure is higher than the first pressure to force the fluid in the fluid channel past the fluidic stop element into the at least one measurement chamber.

### Claim 2 (depends on 1)

The sensing device according to claim 1, wherein
the fluid stop unit comprises a seal arranged at the venting hole for hermetically sealing the venting hole.

### Claim 3 (depends on 2)

The sensing device according to claim 2, wherein the seal is a foil or a membrane.

### Claim 4 (depends on 1)

The sensing device according to claim 1, wherein the fluidic stop element is arranged along the fluid channel for stopping the flow of fluid between the inlet port and the measurement chamber.

### Claim 5 (depends on 4)

The sensing device according to claim 4, wherein the pressure control unit comprises:
a cap arranged at the first section of the device comprising the inlet port, the cap having the opened position and the closed position.

### Claim 6 (depends on 5)

The sensing device according to claim 5, wherein the cap is configured to produce the second pressure when sliding from the opened position to the closed position.

### Claim 7 (depends on 6)

The sensing device according to claim 6, further comprising
a sealing unit for sealing between the cap and the first section, when the cap is at least in the closed position.

### Claim 8 (depends on 4)

The sensing device according to claim 4, wherein the pressure control unit comprises:
a first hole coupled to the first part of the fluid channel for introducing a pressure into the first part of the fluid channel to force the fluid past the fluidic stop unit.

### Claim 9 (depends on 4)

The sensing device according to claim 4, wherein the pressure control unit comprises:
an air chamber coupled to the first part of the fluid channel, wherein the air chamber comprises an elastic cover for covering an opening of the air chamber.

### Claim 10 (depends on 1)

The sensing device according to claim 1, wherein the sensing device is configured to be insertable into an analyzing apparatus for allowing the analyzing apparatus to sense the fluid in the measurement chamber.
