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US 9,040,101 B2Granted
Method to treat diabetes utilizing a gastrointestinal microbiome modulating composition
AssigneeMicroBiome Therapeutics, LLC
InventorsMark L. Heiman, Dean P. Stull, Justin W Peno
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Abstract
Compositions and methods for treating diabetes are presented herein. In particular, the present disclosure teaches compositions and methods for treating diabetes utilizing a gastrointestinal microbiome modulating composition.
Claims30
A method for treating diarrhea associated with administration of metformin in a diabetic human in need thereof, comprising:
- a) administering to the diabetic human a pharmaceutical composition comprising a therapeutically effective amount of metformin;
- and
- b) administering to the diabetic human a therapeutic composition, comprising a therapeutically effective amount of:
- i. purified agave inulin;
- ii. β-glucan extracted from oat;
- and
- iii. blueberry pomace extract comprising at least one polyphenolic compound,
- to effectively treat the diarrhea in the diabetic human.
5 more elements
A method for treating diarrhea in a diabetic human in need thereof, comprising:
- a) administering to the diabetic human a therapeutically effective amount of:
- metformin, purified agave inulin, oat glucan extract, and blueberry pomace extract,
- to effectively treat the diarrhea in the diabetic human.
A method to reduce diarrhea in a Type 2 diabetic human taking a therapeutically effective amount of metformin, comprising:
- a) administering to the Type 2 diabetic human taking metformin, a therapeutically effective amount of a dietary gastrointestinal microbiome modulating composition, comprising, per dose:
- i. at least about 3 grams purified agave inulin;
- ii. at least about 2 grams oat glucan extract;
- and
- iii. blueberry pomace extract comprising at least about 700 mg total polyphenolics,
- wherein said Type 2 diabetic patient experiences reduced episodes of diarrhea.
3 more elements
Dependencies are inferred from the claim text.