# US 9,039,763 B2 · Tissue marking implant

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- Number: US 9,039,763 B2
- Document ID: US9039763B2
- Status: Granted
- Kind: B2
- Application number: 14/166,328
- Filed: 2014-01-28
- Published: 2014-05-22
- Granted: 2015-05-26
- Earliest claimed: 1997-10-10
- Assignees: SenoRx, Inc.
- Applicants: SenoRx, Inc.
- Inventors: John D. Corbitt, Jr.
- Web page: https://patentgrep.com/patent/US9039763B2

## CPC

- A61F 2/12: Mammary prostheses
- A61F 2/0059: {Cosmetic or alloplastic implants (A61F2/10 - A61F2/16, A61F2/28 take precedence)}
- A61F 2/0077: {Special surfaces of prostheses, e.g. for improving ingrowth (A61F2/30767 takes precedence)}
- A61L 27/18: obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
- A61L 27/36: containing ingredients of undetermined constitution or reaction products thereof {, e.g. transplant tissue, natural bone, extracellular matrix (isolated natural compounds, e.g. collagen A61L27/24)}
- A61L 27/56: Porous materials, {e.g. foams or sponges}
- A61L 27/58: Materials at least partially resorbable by the body
- A61B 2090/3908: {Soft tissue, e.g. breast tissue}
- A61F 2210/0004: bioabsorbable
- A61F 2210/0066: shrinkable
- A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C)
- A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K)
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)

## Abstract

An implant for marking an area within a living body includes a matrix material and a marking material. The implant is formable to fit the shape and size of a cavity in the human body. The implant is configured to support tissue surrounding the cavity and to allow in-growth of fibrous tissue into and replace at least a portion of the matrix material.

## Claims

### Claim 1

An implant for marking an area within a surgically formed cavity of a living body, comprising a matrix material and a marking material, the matrix material configured to be elastically compressible and formable to fit the shape and size of the surgically formed cavity in the living body, and configured to fill the cavity and support tissue surrounding the cavity and to allow in-growth of fibrous tissue into and replace at least a portion of the matrix material.

### Claim 2 (depends on 1)

The implant of claim 1, wherein the marking material is a dye, and the matrix material and the marking material are configured such that the marking material leaches into tissue surrounding the surgically formed cavity from the matrix material.

### Claim 3 (depends on 1)

The implant of claim 1, the marking material being contained within the matrix material.

### Claim 4 (depends on 1)

The implant of claim 1, comprising at least one substance selected from the group consisting of medicinal substances, therapeutic substances, and diagnostic substances.

### Claim 5 (depends on 1)

The implant of claim 1, comprising at least one substance selected from the group consisting of radiation materials, antibiotics, chemotherapies, cancer therapeutics, hemostatic materials, and hormone therapeutics.

### Claim 6 (depends on 1)

The implant of claim 1, wherein the matrix material is at least partially biosorbable.

### Claim 7 (depends on 1)

The implant of claim 1, the matrix material includes an outer shell containing both biosorbable material and nonabsorbable material.

### Claim 8 (depends on 7)

The implant of claim 7, wherein the outer shell is configured to form a skeletal outer shell after a resorption of the biosorbable material.

### Claim 9 (depends on 7)

The implant of claim 7, wherein the outer shell comprises compressed matrix material.

### Claim 10 (depends on 1)

The implant of claim 1, wherein the matrix material is self-expanding.

### Claim 11

An implant for insertion into a cavity of a living body, comprising:
a matrix material formable to fit the shape and size of the cavity in the living body, configured to fill the cavity and support tissue surrounding the cavity, the matrix material having an outer shell containing both biosorbable material and nonabsorbable material, wherein the outer shell is configured to form a skeletal outer shell after a resorption of the biosorbable material; and
a marking material coupled to the matrix material.

### Claim 12 (depends on 11)

The implant of claim 11, wherein the nonabsorbable material of the outer shell comprises monofilament polypropylene fibers.

### Claim 13 (depends on 11)

The implant of claim 11, wherein the resorption of the biosorbable material occurs in situ in the cavity of the living body.

### Claim 14 (depends on 11)

The implant of claim 11, wherein the matrix material is configured to be elastically compressible and self-expanding.

### Claim 15 (depends on 11)

The implant of claim 11, wherein the marking material is a dye, and the matrix material and the marking material are configured such that the marking material leaches into tissue surrounding the cavity from the matrix material.

### Claim 16 (depends on 11)

The implant of claim 11, the marking material being contained within the matrix material.

### Claim 17 (depends on 16)

The implant of claim 16, wherein the marking material includes at least one radiographic marker.

### Claim 18 (depends on 11)

The implant of claim 11, comprising at least one substance selected from the group consisting of medicinal substances, therapeutic substances, and diagnostic substances.

### Claim 19 (depends on 11)

The implant of claim 11, comprising at least one substance selected from the group consisting of radiation materials, antibiotics, chemotherapies, cancer therapeutics, hemostatic materials, and hormone therapeutics.
