# US 9,039,650 B2 · Ocular implants with asymmetric flexibility > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 9,039,650 B2 - Document ID: US9039650B2 - Status: Granted - Kind: B2 - Application number: 14/246,363 - Filed: 2014-04-07 - Published: 2014-07-31 - Granted: 2015-05-26 - Earliest claimed: 2007-09-24 - Assignees: Ivantis, Inc. - Applicants: Ivantis, Inc. - Inventors: Andrew T. Schieber; Charles L. Euteneuer - Web page: https://patentgrep.com/patent/US9039650B2 ## CPC - A61F 9/00781: {Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment (drainage implants in general A61M27/002)} - A61F 2/14: Eye parts, e.g. lenses or corneal implants; Artificial eyes - A61F 2/15: {Implant having one or more holes, e.g. for nutrient transport, for facilitating handling} - A61P 27/02: Ophthalmic agents - A61F 2220/0008: Fixation appliances for connecting prostheses to the body - A61F 2250/0067: Means for introducing or releasing pharmaceutical products into the body - A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C) - A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS ## Abstract An ocular implant having an inlet portion and a Schlemm's canal portion distal to the inlet portion, the inlet portion being disposed at a proximal end of the implant and sized and configured to be placed within an anterior chamber of a human eye, the Schlemm's canal portion being arranged and configured to be disposed within Schlemm's canal of the eye when the inlet portion is disposed in the anterior chamber. ## Claims ### Claim 1 An ocular implant comprising an inlet portion and a Schlemm's canal portion distal to the inlet portion, the inlet portion being disposed at a proximal end of the implant and sized and configured to be placed within an anterior chamber of a human eye, the inlet portion having an inlet adapted to be in fluid communication with the anterior chamber, the Schlemm's canal portion having a diameter between 0.005 inches and 0.04 inches, the Schlemm's canal portion comprising: a central channel in fluid communication with the inlet, the central channel extending longitudinally in the Schlemm's canal portion; a first element disposed along the central channel; a second element disposed along the central channel distal to the first element; a third element disposed along the central channel distal to the first element and proximal to the second; a fourth element disposed along the central channel distal to the second element; the first, second, third and fourth elements each comprising two edges partially defining an elongate opening in fluid communication with the central channel, each of the first, second, third and fourth elements having circumferential extents less than 360 degrees so that the elongate opening extends continuously along the first, second, third and fourth elements, wherein each of the first, second, third, and fourth elements have an arc length, the arc lengths of the circumferential extents of the first and second elements being less than the arc lengths of the circumferential extents of the third and fourth elements; the Schlemm's canal portion being arranged and sized to be disposed within Schlemm's canal of the eye when the inlet portion is disposed in the anterior chamber, such that the entire ocular implant is sized to be implanted within the eye. ### Claim 2 (depends on 1) The ocular implant of claim 1 wherein the first, second, third and fourth elements are disposed in a cylindrical volume having a curved longitudinal axis. ### Claim 3 (depends on 2) The ocular implant of claim 2 wherein the Schlemm's canal portion has a first flexibility when bent along a first plane defined by the curved longitudinal axis and a second flexibility different from the first flexibility when bent along a second plane that intersects the first plane and is not coincident with the first plane. ### Claim 4 (depends on 3) The ocular implant of claim 3 wherein the Schlemm's canal portion has a shape that is symmetric about the first plane. ### Claim 5 (depends on 3) The ocular implant of claim 3 wherein the first plane passes through the elongate opening. ### Claim 6 (depends on 2) The ocular implant of claim 2 wherein the elongate opening is disposed on a radially outward portion of the cylindrical volume. ### Claim 7 (depends on 1) The ocular implant of claim 1 further comprising openings through the third and fourth elements in fluid communication with the central channel. ### Claim 8 (depends on 7) The ocular implant of claim 7 wherein outer surfaces of the inlet portion and the Schlemm's canal portion define a volume, the elongate opening and the openings through the third and fourth elements extending over more than 50% of the volume. ### Claim 9 (depends on 8) The ocular implant of claim 8 wherein the volume is a cylindrical volume. ### Claim 10 (depends on 8) The ocular implant of claim 8 wherein the volume is curved. ### Claim 11 (depends on 1) The ocular implant of claim 1 wherein material coverage in cross-sections perpendicular to a longitudinal axis of the ocular implant is less than 50% over greater than 90% of the implant. ### Claim 12 (depends on 1) The ocular implant of claim 1 wherein the ocular implant defines a cylindrical volume having a curved longitudinal axis and extending through an arcuate range between 60 degrees and 180 degrees. ### Claim 13 (depends on 1) The ocular implant of claim 1 wherein the first element has a width to thickness ratio greater than 2. ### Claim 14 (depends on 13) The ocular implant of claim 13 wherein the second element has a width to thickness ratio greater than 2. ### Claim 15 (depends on 1) The ocular implant of claim 1 wherein the third element has a width to thickness ratio greater than 4. ### Claim 16 (depends on 15) The ocular implant of claim 15 wherein the fourth element has a width to thickness ratio greater than 4. ### Claim 17 (depends on 1) The ocular implant of claim 1 wherein each of the first and second elements has a width to thickness ratio greater than 2 and each of the third and fourth elements has a width to thickness ratio greater than 4.