# US 9,039,622 B2 · Image generation system

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- Number: US 9,039,622 B2
- Document ID: US9039622B2
- Status: Granted
- Kind: B2
- Application number: 13/803,657
- Filed: 2013-03-14
- Published: 2014-07-17
- Granted: 2015-05-26
- Earliest claimed: 2013-01-16
- Assignees: National Taiwan University
- Applicants: National Taiwan University
- Inventors: Pai-Chi Li; Bao-Yu Hsieh
- Web page: https://patentgrep.com/patent/US9039622B2

## CPC

- A61B 8/44: {Constructional features of the ultrasonic, sonic or infrasonic diagnostic device}
- A61B 5/0035: {adapted for acquisition of images from more than one imaging mode, e.g. combining MRI and optical tomography}
- A61B 5/0095: {by applying light and detecting acoustic waves, i.e. photoacoustic measurements}
- A61B 8/4416: {related to combined acquisition of different diagnostic modalities, e.g. combination of ultrasound and X-ray acquisitions}
- A61B 8/4477: {using several separate ultrasound transducers or probes}
- A61B 8/5261: {combining images from different diagnostic modalities, e.g. ultrasound and X-ray}
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)

## Abstract

An image generation system is provided, the system generating an ultrasound image and a photo-acoustic image of an object and including a dual-wavelength laser source, an optical filter, and an optical-based ultrasound sensor. The laser source generates a first laser pulse with a first wavelength or a second laser pulse with a second wavelength. The optical filter almost completely absorbs the energy of the first laser pulse and by the photo-acoustic effect, generates and transmits an ultrasound to the object so the object scatters and reflects the ultrasound. The second laser pulse almost completely penetrates the optical filter and is transmitted to the object so the object absorbs the energy of the second laser pulse, generates and sends a photo-acoustic signal. The optical-based ultrasound sensor receives the ultrasound and the photo-acoustic signal to generate the ultrasound image and the photo-acoustic image of the object.

## Claims

### Claim 1

An image generation system, the system generating an ultrasound image and a photo-acoustic image of an object, the system comprising:
a laser source outputting a first laser pulse having a first wavelength and a second laser pulse having a second wavelength;
an optical filter receiving and filtering the first laser pulse and the second laser pulse, the optical filter almost completely absorbing the energy of the first laser pulse, generating and transmitting a photoacoustics-based ultrasound to the object, the object scattering and reflecting the photoacoustics-based ultrasound so an echo is generated; the optical filter almost completely transmitting the second laser pulse so the second laser pulse is transmitted to the object, the object scattering and reflecting a photo-acoustic wave; and
an optical-based ultrasound sensor disposed close to the optical filter, the optical-based ultrasound sensor receiving the echo to generate the ultrasound image of the object and receiving the photo-acoustic wave to generate the photo-acoustic image of the object.

### Claim 2 (depends on 1)

The system according to claim 1, wherein the optical-based ultrasound sensor includes a polymer microring resonator, the polymer microring including a one-dimensional array receiver or a two-dimensional array receiver.

### Claim 3 (depends on 1)

The system according to claim 1, further comprising an optical detector and an AD converter, wherein the optical detector is coupled to an output end of the optical-based ultrasound sensor and the AD converter is electrically connected to the optical detector, the optical detector detecting the light intensity of the output end of the optical-based ultrasound sensor so as to generate and send an analog detected signal to the AD converter, the AD converter digitalizing the analog detected signal so as to generate and send a digital detected signal.

### Claim 4 (depends on 1)

The system according to claim 1, further comprising a continuous wavelength tunable laser coupled to an input end of the optical-based ultrasound sensor.

### Claim 5 (depends on 3)

The system according to claim 3, further comprising a signal processing device electrically connected to the AD converter, the signal processing device receiving the digital detected signal and recovering at least an ultrasound waveform or a waveform of photo-acoustic signal.

### Claim 6 (depends on 5)

The system according to claim 5, wherein the signal processing device is selected from the group of a desktop computer, a notebook computer and a tablet computer.

### Claim 7 (depends on 1)

The system according to claim 1, wherein the optical filter absorbs the first laser pulse with a high absorption rate and transmits the second laser pulse with a high transmission rate; the absorption rate and the transmission rate are selected from 90% to 100%.

### Claim 8 (depends on 1)

The system according to claim 1, further comprising a scanning motor coupled to the laser source, the optical filter and the optical-based ultrasound sensor, the scanning makes 2D or 3D image of the object.

### Claim 9 (depends on 1)

The system according to claim 1, wherein the laser source is selected from the group of a tunable pulsed laser, and an Nd:YAG laser coupled with a Ti:Sapphire laser.

### Claim 10 (depends on 1)

The system according to claim 1, wherein the optical filter is selected from the group of a low pass filter, a band pass filter and a high pass filter.
