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US 9,035,044 B2Granted
L-proline and citric acid co-crystals of (2S, 3R, 4R, 5S,6R)-2-(3-((5-(4-fluorophenyl)thiopen-2-yl)methyl)4-methylphenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
AssigneeJanssen Pharmaceutica NV
InventorsMinh Nguyen, Edwin A. Collier
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Abstract
The present invention is directed to L-proline and citric acid co-crystals of (2S,3R,4R,5S,6R)-2-(3-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol, pharmaceutical compositions containing said co-crystals and their use in the treatment glucose-related disorders such as Type 2 diabetes mellitus and Syndrome X.
Claims6
An L-proline co-crystal of a compound of formula (I-X)
A citric acid co-crystal of a compound of formula (I-X)
Dependencies are inferred from the claim text.