Omega-3 enriched fish oil-in-water parenteral nutrition emulsions
AssigneeStable Solutions LLC
InventorDavid F. Driscoll
Life of this patent
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Abstract
An emulsion is provided including: an oil component and a water component, the oil component including: fish oil triglycerides in an amount of about 60% to about 90% based on the weight of the oil component; wherein the fish oil triglycerides include omega-3 fatty acids, expressed as triglycerides, in an amount of at least 60%, based on the total weight of the fatty acids of the fish oil triglycerides; wherein the fish oil triglycerides include a total amount of EPA and DHA, expressed as triglycerides, of at least 45%, based on the total weight of the fatty acids of the fish oil triglycerides; and, at least one medium-chain triglyceride, wherein a total amount of the at least one medium-chain triglyceride is from about 10% to about 40% based on the weight of the oil component.
Claims25
An oil-in-water emulsion comprising:
- a) fish oil triglycerides consisting of glycerol which is esterified with fatty acids wherein said fatty acids comprise EPA and DHA in an amount of at least 45% by weight of said fatty acids and the total amount of omega-3 fatty acids is at least 60% by weight of said fatty acids, and
- b) at least one medium chain triglyceride oil, and
- wherein the fish oil triglycerides are present in an amount of at least 51% by weight based on the total weight of the oil component, and the medium chain triglycerides are present in an amount of 10% to 49% by weight based on the total weight of the oil component.
An emulsion comprising:
- an oil component and a water component, the oil component comprising:
- fish oil triglycerides in an amount of about 60% to about 90% based on the weight of the oil component;
- wherein the fish oil triglycerides comprise omega-3 fatty acids, expressed as triglycerides, in an amount of at least 60%, based on the total weight of the fatty acids of the fish oil triglycerides;
- wherein the fish oil triglycerides comprise a total amount of EPA and DHA, expressed as triglycerides, of at least 45%, based on the total weight of the fatty acids of the fish oil triglycerides;
- and,
- at least one medium-chain triglyceride oil, wherein a total amount of the at least one medium-chain triglyceride oil is from about 10% to about 40% based on the weight of the oil component.
An oil composition suitable for use as an oil component of an oil-in-water emulsion, comprising:
- fish oil triglycerides in an amount of about 60% to about 90% based on the weight of the composition;
- wherein the fish oil triglycerides comprise omega-3 fatty acids, expressed as triglycerides, in an amount of at least 60%, based on the total weight of the fatty acids of the fish oil triglycerides;
- wherein the fish oil triglycerides comprise a total amount of EPA and DHA, expressed as triglycerides, of at least 45%, based on the total weight of the fatty acids of the fish oil triglycerides;
- and,
- at least one medium-chain triglyceride oil, wherein a total amount of the at least one medium-chain triglyceride oil is from about 10% to about 40% based on the weight of the composition.
Dependencies are inferred from the claim text.