Use of cannabinoids in combination with an anti-psychotic medicament
AssigneesGW Pharma Limited, Otsuka Pharmaceutical Co., Ltd.
InventorsTetsuro Kikuchi, Kenji Maeda, Geoffrey Guy, Philip Robson, Colin Stott
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Abstract
The present invention relates to the use of one or more cannabinoids in combination with one or more anti-psychotic medicaments for use in the prevention or treatment of psychosis and psychotic disorders. Preferably the one or more cannabinoids are taken from the group: cannabidiol (CBD); cannabidiolic acid (CBDA); tetrahydrocannbidivarin (THCV); tetrahydrocannbidivarinin acid (THCVA); cannabichromene (CBC); cannabichromenic acid (CBCA); cannabigerol (CBG) and cannabigerolic acid (CBGA). Preferably the anti-psychotic medication is an atypical anti-psychotic medication.
Claims21
A method for the treatment of psychosis or a psychotic disorder, which comprises administering to a subject in need thereof a therapeutically effective amount of THCV and/or CBD, in combination with a sub-effective dose of an atypical anti-psychotic medicament, wherein the THCV and/or CBD are administered separately, sequentially or simultaneously to the atypical anti-psychotic medicament so as to reduce or remove undesirable side effects of the atypical anti-psychotic medicament and/or provide additional anti-psychotic effects, wherein the atypical anti-psychotic medicament is a dopamine-serotonin system stabilizer.
A method for the treatment of psychosis or a psychotic disorder in a child or juvenile, which comprises administering to a subject in need thereof a therapeutically effective amount of THCV and/or CBD, in combination with a sub-effective dose of an atypical anti-psychotic medicament, wherein the THCV and/or CBD are administered separately, sequentially or simultaneously to the atypical anti-psychotic medicament so as to reduce or remove undesirable side effects of the atypical anti-psychotic medicament and/or provide additional anti-psychotic effects, wherein the atypical anti-psychotic medicament is a dopamine-serotonin system stabilizer.
Dependencies are inferred from the claim text.