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US 9,017,699 B2Granted
Adjuvancy and immune potentiating properties of natural products of Onchocerca volvulus
AssigneeNew York Blood Center, Inc.
InventorsAngus J. MacDonald, Sara Lustigman
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Abstract
The present invention relates to a method for potentiating a specific immune response to an antigen in a mammal in need thereof. The method comprises administering to the mammal an effective amount of Ov-ASP, or at least one subunit of Ov-ASP, and an antigenic moiety.
Claims6
An immunogenic composition comprising an isolated antigen unrelated to Onchocerca volvulus activation-associated secreted protein (Ov-ASP), the antigen mixed with a specific immune response-potentiating effective amount of an isolated Ov-ASP adjuvant comprising amino acids 14-223 of SEQ ID NO:
- 1, wherein the antigen is from a pathogenic microorganism against which a mammal is in need of an immune response.
Dependencies are inferred from the claim text.