Ophthalmic and otorhinolaryngological device materials

A polymeric ophthalmic or otorhinolaryngological device material comprising

• a) 70 to 98% (w/w) of a monofunctional monomer of formula [1]:
• wherein
• B═—O(CH2)n—, —(OCH2CH2)n—, —NH(CH2)n—, or —NCH3(CH2)n—;
• R1═H, CH3, CH2CH3, or CH2OH;
• n=0-12;
• A=C6H5 or O(CH2)mC6H5, where the C6H5 group is optionally substituted with —(CH2)nH, —O(CH2)nH, —CH(CH3)2, —C6H5, —OC6H5, —CH2C6H5, F, Cl, Br, or I;
• and
• m=0-18;
• b) a difunctional cross-linking monomer of formula [2]:
• wherein
• R2, R3 independently=H, CH3, CH2CH3, or CH2OH;
• W, W′ independently=O(CH2)d, NH(CH2)d, NCH3(CH2)d, O(CH2)dC6H4, O(CH2CH2O)dCH2, O(CH2CH2CH2O)dCH2, O(CH2CH2CH2CH2O)dCH2, or nothing;
• J=(CH2)a, O(CH2CH2O)b, O, or nothing, provided that if W and W′=nothing, then J ≠ nothing;
• d=0-12;
• a=1-12;
• and
• b=1-24;
• and
• c) 0.5 to 15% (w/w) of a copolymer additive of formula [3]:
• wherein for formula [3]:
• D=OCH2CH2S, SCH2C═O, CH3CH(OH)CH2S, SCH2CH(OH)CH2O, S(CH2)11O, S(CH2)10C═O, S(CH2)14C═O, S(CH2)15C═O, SC6H4CH2O, CH3CH(S)C═O, S(CH2CH2CH2)O, CH3CH(S)CH(O)CH3, OCH2CH2C(CH3)2S, SCH2CH2C═O, S(CH2)4O, SC6H4CH2C═O, SC6H4C═O, S(CH2)11C═O, CH3CH(O)CH(S)CH3, SC6H4C═O, S(CH2)6OC6H4CH2O, S(CH2)6O, S(CH2)5C═O, S(CH2)7C═O, S(CH2)9O, C(CH3)2C(═O)NHCH2CH2O, C(CH3)2C(═NH)NHCH2CH2C═O, C(CH3)2C(═O)NHCH(CH2CH3)(CH2O), C(CH3)2CN, C(CH3)(CN)CH2C(OCH3)(CH3CH3) , C(CH3)2C(═O)NHCH2CH═CH2, C(CH3)(CN)CH2C(CH3)2(OCH3), C(CH3)(CN)CH2CH(CH3)2, C(CH3)2C(═O)OCH3, C(CH3)(CN)CH2CH3, C(CN)(CH2)5, C(CH3)2C(═O)NHCH2CH2CH2CH3, or C(CH3)2C(═O)NHC6H11;
• E=nothing, O(CH2)nNH, (OCH2CH2)nNH, O(CH2)nNHC═O, HN(CH2)nNH, OH, or H;
• provided that if D=C(CH3)2CN, C(CH3)(CN)CH2C(OCH3)(CH3CH3), C(CH3)2C(═O)NHCH2CH═CH2, C(CH3)(CN)CH2C(CH3)2(OCH3), C(CH3)(CN)CH2CH(CH3)2, C(CH3)2C(═O)OCH3, C(CH3)(CN)CH2CH3, C(CN)(CH2)5, C(CH3)2C(═O)NHCH2CH2CH2CH3, or C(CH3)2C(═O)NHC6H11, then E=F=nothing;
• n=1-5;
• if D≠C(CH3)2CN, C(CH3)(CN)CH2C(OCH3)(CH3CH3), C(CH3)2C(═O)NHCH2CH═H2, C(CH3)(CN)CH2C(CH3)2(OCH3), C(CH3)(CN)CH2CH(CH3)2, C(CH3)2C(O)OCH3, C(CH3)(CH)CH2CH3, C(CN)(CH2)5, C(CH3)2C(═O)NHCH2CH2CH2CH3, or C(CH3)2C(O)NHC6H11 then
• if E=H or OH, then F=nothing;
• if E≠H or OH, then F═C(═O)C(CH3)═CH2, C(═O)CH═CH2, C(═O)C(CH2CH3)═CH2, C(═O)C(CH2OH)═CH2, C(═O)NHCH2CH2OC(═O)C(CH3)═CH2, or C(═O)NHC(CH3)2C6H4C(═CH2)CH3;
• R4, R5, and R6 independently=H or CH3;
• t, u, and v represent molar fraction values and t+u+v=1;
• t and u independently=0-0.95;
• provided that t+u=0.8-0.95;
• v=0.05-0.2;
• W═H, CH3, C(═O)C(CH3)═CH2, C(═O)CH═CH2, C(═O)C(CH2CH3)═CH2, C(═O)C(CH2OH)═CH2, C(═O)NHCH2CH2OC(═O)C(CH3)═CH2, or C(═O)NHC(CH3)2C6H4C(═CH2)CH3;
• provided that if F=nothing, then W═C(═O)C(CH3)═CH2, C(═O)CH═CH2, C(═O)C(CH2CH3)═CH2, C(═O)C(CH2OH)═CH2, C(═O)NHCH2CH2OC(═O)C(CH3)═CH2, or C(═O)NHC(CH3)2C6H4C(═CH2)CH3;
• y1, y2, and y3 independently=4-200;
• and
• x=1-100;
• wherein the polymeric device material has an equilibrium water content of 0.5-3.0%.