Medical apparatus for extracorporeal blood treatment and method for determining a blood parameter value in a medical apparatus thereof

Controller for a medical apparatus (1), said medical apparatus comprising at least one machine (2) for extracorporeal blood treatment connectable to at least a blood treatment unit (3), to an extracorporeal blood line (4) having a withdrawal branch (5) adapted to withdraw blood from a patient access (6) and to bring the withdrawn blood to the blood treatment unit (3) and a return branch (7) adapted to bring the blood from the blood treatment unit (3) to the patient, and to at least one sensor (8) associated to the extracorporeal line (4) and adapted to provide a measure related to a blood parameter value in the blood circulating in the extracorporeal blood line (4), wherein said blood parameter value depends on the blood characteristic of the specific patient and is selected in the group comprising:

• blood density, blood hematocrit, blood hemoglobin concentration, mean blood cellular volume;
• the medical apparatus including at least one storage memory (10) for storing measures related to the blood parameter value, each measure being made through one of the sensors (8) of said prefixed number of machines (2) and each corresponding to different treatment sessions of patients on said prefixed number of machines (2), the controller being configured for performing the following steps:
• taking from the storage memory (10) a plurality of measures related to the blood parameter value, each measure being made through one of the sensors (8) of said prefixed number of machines (2) at different patient treatment sessions, said plurality of measures relating to the same patient;
• receiving at least an actual control value of the same blood parameter relating to the same patient, said actual control value being measured at a monitoring time;
• wherein said actual control value is a real absolute value of the blood parameter measured through laboratory measurements;
• determining a correcting factor function of a difference between a prefixed number of measures made through the sensors (8) and the actual control value of the blood parameter, obtaining an actual value of said blood parameter by varying at least the last measure made through the sensor by means of the correcting factor;
• interpolating said plurality of measures made through the sensor (8) for obtaining an interpolated curve (12) defining a blood parameter trend along time;
• determining the correcting factor as a difference between the actual control value of the blood parameter and a time-corresponding value of the blood parameter in the interpolated curve;
• and
• translating at least a last part (12a) of the interpolated curve (12) by means of the correcting factor, the last part (12a) of the interpolated curve (12) comprising at least the last two measured blood parameter values.

Method for determining a blood parameter value in a medical apparatus comprising:

• at least a machine (2) for extracorporeal blood treatment;
• at least a blood treatment unit (3);
• an extracorporeal blood line (4) having a withdrawal branch (5) adapted to withdraw blood from a patient access (6) and to bring the withdrawn blood to the blood treatment unit (3) and a return branch (7) adapted to bring the blood from the blood treatment unit (3) to the patient;
• at least one sensor (8) associated to the extracorporeal line (4) and adapted to provide a measure related to a blood parameter value in the blood circulating in the extracorporeal blood line (4);
• wherein said blood parameter value depends on the blood characteristic of the specific patient and is selected in the group comprising:
• blood density, blood hematocrit, blood hemoglobin concentration, mean blood cellular volume;
• a control unit (9);
• at least one storage memory (10) for storing measures related to the blood parameter value, each measure being made through one of the sensors (8) of said prefixed number of machines (2) and corresponding to different treatment sessions of patients on said prefixed number of machines (2);
• the method comprising the following steps:
• taking from the storage memory (10) a plurality of measures related to the blood parameter, each measure being made through one sensors (8) of said prefixed number of machines at different patient treatment sessions;
• said measures relating to the same patient;
• receiving at least an actual control value of the same blood parameter relating to the same patient, said actual control parameter being measured at a monitoring time;
• wherein said actual control value is a real absolute value of the blood parameter measured through laboratory measurements;
• determining a correcting factor function of a difference between a prefixed number of measures made through the sensors (8) and the actual control value of the blood parameter for obtaining a value of said blood parameter by varying at least the last measure made through the sensor by means of the correcting factor;
• interpolating said plurality of measures made through the sensor (8) for obtaining an interpolated curve (12) defining a blood parameter trend along time;
• determining the correcting factor as a difference between the actual control value of the blood parameter and a time-corresponding value of the blood parameter in the interpolated curve;
• and
• translating at least a last part (12a) of the interpolated curve (12) by means of the correcting factor, the last part (12a) of the interpolated curve (12) comprising at least the last two measured blood parameter values.

Method for determining a blood parameter value in a medical apparatus comprising:

• at least a machine (2) for extracorporeal blood treatment;
• at least a blood treatment unit (3);
• an extracorporeal blood line (4) having a withdrawal branch (5) adapted to withdraw blood from a patient access (6) and to bring the withdrawn blood to the blood treatment unit (3) and a return branch (7) adapted to bring the blood from the blood treatment unit (3) to the patient;
• at least one sensor (8) associated to the extracorporeal line (4) and adapted to provide an indirect measure of a biological parameter of the blood circulating in the extracorporeal blood line (4);
• a control unit (9);
• at least one storage memory (10) for storing the indirect measures of the biological blood parameter, each measure being made through one of the sensors (8) of said prefixed number of machines (2) and corresponding to different treatment sessions of patients on said prefixed number of machines (2);
• the method comprising the following steps:
• taking from the storage memory (10) a plurality of indirect measures of the blood parameter, each indirect measure being made through one sensors (8) of said prefixed number of machines at different patient treatment sessions;
• said measures relating to the same patient;
• receiving at least a direct measure of the same blood parameter relating to the same patient measured through laboratory measurements, said direct measure being measured at a monitoring time;
• determining a correcting factor function of a difference between a prefixed number of indirect measures made through the sensors (8) and the direct laboratory measure of the blood parameter for obtaining a value of said blood parameter by varying at least the last measure made through the sensor by means of the correcting factor;
• interpolating said plurality of indirect measures made through the sensor (8) for obtaining an interpolated curve (12) defining a blood parameter trend along time;
• determining the correcting factor as a difference between the direct laboratory measure of the blood parameter and a time-corresponding value of the blood parameter of the interpolated curve;
• translating at least a last part (12a) of the interpolated curve (12) by means of the correcting factor, the last part (12a) of the interpolated curve (12) comprising at least the last two indirectly measured blood parameter values.

Medical apparatus (1) comprising:

• at least one machines (2) for extracorporeal blood treatment having;
• at least a blood treatment unit (3);
• an extracorporeal blood line (4) having a withdrawal branch (5) adapted to withdraw blood from a patient access (6) and to bring the withdrawn blood to the blood treatment unit (3) and a return branch (7) adapted to bring the blood from the blood treatment unit (3) to the patient;
• at least one sensor (8) associated to the extracorporeal line (4) and adapted to provide a measure related to a blood parameter value in the blood circulating in the extracorporeal blood line (4);
• a control unit (9);
• at least one storage memory (10) for storing measures related to the blood parameter value, each measure being made through one of the sensors (8) of said prefixed number of machines (2) and each corresponding to different treatment sessions of patients on said prefixed number of machines (2);
• the control unit (9) being configured for performing the following steps:
• taking from the storage memory (10) a plurality of measures related to the blood parameter value, each measure being made through one of the sensors (8) of said prefixed number of machines (2) at different patient treatment sessions, said plurality of measures relating to the same patient;
• receiving at least an actual control value of the same blood parameter relating to the same patient, said actual control value being measured at a monitoring time;
• determining a correcting factor function of a difference between a prefixed number of measures made through the sensors (8) and the actual control value of the blood parameter, obtaining an actual value of said blood parameter by varying at least the last measure made through the sensor by means of the correcting factor;
• interpolating said plurality of measures made through the sensor (8) for obtaining an interpolated curve (12) defining a blood parameter trend along time;
• determining the correcting factor as a difference between the actual control value of the blood parameter and a time-corresponding value of the blood parameter in the interpolated curve;
• translating at least the last part (12a) of the interpolated curve (12) by means of the correcting factor, the last part (12a) of the interpolated curve (12) comprising at least the last two measured blood parameter values;
• displaying either the at least last part of the translated interpolated curve (13) or the at least last two translated blood parameter values.

Medical apparatus (1) comprising:

• at least one machines (2) for extracorporeal blood treatment having;
• at least a blood treatment unit (3);
• an extracorporeal blood line (4) having a withdrawal branch (5) adapted to withdraw blood from a patient access (6) and to bring the withdrawn blood to the blood treatment unit (3) and a return branch (7) adapted to bring the blood from the blood treatment unit (3) to the patient;
• at least one sensor (8) associated to the extracorporeal line (4) and adapted to provide a measure related to a blood parameter value in the blood circulating in the extracorporeal blood line (4);
• a control unit (9);
• at least one storage memory (10) for storing measures related to the blood parameter value, each measure being made through one of the sensors (8) of said prefixed number of machines (2) and each corresponding to different treatment sessions of patients on said prefixed number of machines (2);
• the control unit (9) being configured for performing the following steps:
• taking from the storage memory (10) a plurality of measures related to the blood parameter value, each measure being made through one of the sensors (8) of said prefixed number of machines (2) at different patient treatment sessions, said plurality of measures relating to the same patient;
• receiving at least an actual control value of the same blood parameter relating to the same patient, said actual control value being measured at a monitoring time;
• determining a correcting factor function of a difference between a prefixed number of measures made through the sensors (8) and the actual control value of the blood parameter, obtaining an actual value of said blood parameter by varying at least the last measure made through the sensor by means of the correcting factor;
• wherein the each machine (2) includes a processor (19) configured for:
• validating a first stable measured blood parameter value in a single treatment session and
• storing said validated first stable measure in the storage memory (10) together with a time information and a patient identification data;
• wherein the processor (19) is configured for validating the first stable measured blood parameter value in the single treatment session by:
• obtaining at least a first and a second, and optionally a third measure, of the blood parameter value;
• determining a difference between the first measure and the second measure, and optionally between the first and the third measure or the second and the third measure;
• comparing said difference with a prefixed threshold;
• validating the measure if an absolute value of the difference is below said threshold.

Method for determining a blood parameter value in a medical apparatus comprising:

• at least a machine (2) for extracorporeal blood treatment;
• at least a blood treatment unit (3);
• an extracorporeal blood line (4) having a withdrawal branch (5) adapted to withdraw blood from a patient access (6) and to bring the withdrawn blood to the blood treatment unit (3) and a return branch (7) adapted to bring the blood from the blood treatment unit (3) to the patient;
• at least one sensor (8) associated to the extracorporeal line (4) and adapted to provide a measure related to a blood parameter value in the blood circulating in the extracorporeal blood line (4);
• a control unit (9);
• at least one storage memory (10) for storing measures related to the blood parameter value, each measure being made through one of the sensors (8) of said prefixed number of machines (2) and corresponding to different treatment sessions of patients on said prefixed number of machines (2);
• the method comprising the following steps:
• taking from the storage memory (10) a plurality of measures related to the blood parameter, each measure being made through one sensors (8) of said prefixed number of machines at different patient treatment sessions;
• said measures relating to the same patient;
• receiving at least an actual control value of the same blood parameter relating to the same patient, said actual control parameter being measured at a monitoring time;
• determining a correcting factor function of a difference between a prefixed number of measures made through the sensors (8) and the actual control value of the blood parameter for obtaining a value of said blood parameter by varying at least the last measure made through the sensor by means of the correcting factor;
• interpolating said plurality of measures made through the sensors (8) for obtaining an interpolated curve (12) defining a blood parameter trend a long time;
• determining the correcting factor as a difference between the actual control value of the blood parameter and a time-corresponding value of the blood parameter in the interpolated curve;
• translating at least the last part (12a) of the interpolated curve (12) by means of the correcting factor, the last part (12a) of the interpolated curve (12) comprising at least the last two measured blood parameter values;
• displaying either the translated interpolated curve (13) or the translated blood parameter values.

Method for determining a blood parameter value in a medical apparatus comprising:

• at least a machine (2) for extracorporeal blood treatment;
• at least a blood treatment unit (3);
• an extracorporeal blood line (4) having a withdrawal branch (5) adapted to withdraw blood from a patient access (6) and to bring the withdrawn blood to the blood treatment unit (3) and a return branch (7) adapted to bring the blood from the blood treatment unit (3) to the patient;
• at least one sensor (8) associated to the extracorporeal line (4) and adapted to provide a measure related to a blood parameter value in the blood circulating in the extracorporeal blood line (4);
• a control unit (9);
• at least one storage memory (10) for storing measures related to the blood parameter value, each measure being made through one of the sensors (8) of said prefixed number of machines (2) and corresponding to different treatment sessions of patients on said prefixed number of machines (2);
• the method comprising the following steps:
• taking from the storage memory (10) a plurality of measures related to the blood parameter, each measure being made through one sensors (8) of said prefixed number of machines at different patient treatment sessions;
• said measures relating to the same patient;
• receiving at least an actual control value of the same blood parameter relating to the same patient, said actual control parameter being measured at a monitoring time;
• determining a correcting factor function of a difference between a prefixed number of measures made through the sensors (8) and the actual control value of the blood parameter for obtaining a value of said blood parameter by varying at least the last measure made through the sensor by means of the correcting factor:
• validating the first stable measured blood parameter value in a single treatment session;
• storing said validated first stable measure in the storage memory (10) together with a time information and a patient identification data;
• wherein the step of validating is performed by:
• obtaining at least a first measure and second measure, and optionally a third measure, of the blood parameter value;
• determining the difference between the first measure and the second measure, and optionally between the first and the third measure or second and third measure;
• comparing an absolute value of said difference with a prefixed threshold;
• validating the measure if the absolute value of the difference is below said thresholds.