US 9,000,193 B2Granted

Process for the preparation of cabazitaxel

AssigneeFresenius Kabi Oncology Limited

InventorsSaswata Lahiri, Nitin Gupta, Abul Azim, Nilendu Panda, Bhuwan Bhaskar Mishra, Sunil Sanghani

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Abstract

The present invention discloses a process for the preparation of 4-acetoxy-2α-benzoyloxy-5β,20-epoxy-1-hydroxy-7β,10β-dimethoxy-9-oxotax-11-en-13α-yl(2R,3S)-3-tert-butoxycarbonylamino-2-hydroxy-3-phenyl-propionate Cabazitaxel (I).

Claims2

Dependent claims

A compound of Formula (XII)

Dependencies are inferred from the claim text.

Facts

Application: 14/533,412Filed 5 Nov 2014 · division
Priority: IN 2794/DEL/201126 Sep 2011
Published: US 2015/0057454 A126 Feb 2015
Granted: 7 Apr 2015
Term ends: Not estimatedThe source records don’t support an estimate.

Classification4 codes

C07F 7/1804
Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages: compounds having Si-O-C linkages
C07D 305/14
Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms: condensed with carbocyclic rings or…
C07F
Acyclic, carbocyclic or heterocyclic compounds containing elements other than carbon, hydrogen, halogen
C07D
Heterocyclic compounds

Family

Application13/625,155Parent of this division · filed 24 Sep 2012
US 2015/0057454 A1Pre-grant publication · published 26 Feb 2015
US 8,901,327 B2Parent of this division
US 2014/0058119 A1Published application
US 9,000,193 B2This patent

From the US filing history. Foreign family members aren’t listed.

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