Parasiticidal compositions comprising benzimidazole derivatives, methods and uses thereof
AssigneeMerial Limited
InventorCharles Q Meng
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Abstract
The invention relates to oral, topical or injectable compositions for combating liver fluke parasites in mammals, comprising at least one benzimidazole derivative active agent. The invention also provides for an improved method for eradicating and controlling liver fluke parasite infections and infestations in a mammal comprising administering the compositions of the invention to the mammal in need thereof.
Claims32
A compound of the formula:
- wherein:
- R1 is (C1-C6)-alkyl, substituted with two or more halogens;
- R2 is H or halogen;
- R3 is a bi- or tri-halogen substituted phenyl;
- R4 is H or halogen;
- and
- R5 is H or halogen.
A compound that is 6-chloro-5-(4-chlorophenyl)-2-trifluoromethylbenzimidazole.
A compound that is 6-chloro-5-(2,3-dichlorophenoxy)-2-heptafluoropropylbenzimidazole.
A compound that is 5-chloro-6-(2,4-dichlorophenoxy)-2-(heptafluoropropyl)-1H-1,3-benzodiazole.
Dependencies are inferred from the claim text.