Ring-fused heterocyclic derivative

A compound represented by the general formula (IA) or a pharmaceutically acceptable salt thereof,

• wherein R1A represents optionally substituted lower alkyl, optionally substituted lower alkenyl, optionally substituted cycloalkyl, optionally substituted lower alkoxy, an optionally substituted aromatic heterocyclic group, an optionally substituted aliphatic heterocyclic group, optionally substituted aralkyl, —C(═O)R4 (wherein R4 represents optionally substituted lower alkyl, optionally substituted aralkyl, optionally substituted cycloalkyl, or an optionally substituted aliphatic heterocyclic group), —C(═O)OR4 (wherein R4 has the same definition as described above), —C(═O)NR5R6 (wherein R5 and R6 may be the same or different, and each represents a hydrogen atom, optionally substituted lower alkyl, or optionally substituted aralkyl), —NR7C(═O)OR4 (wherein R4 has the same definition as described above, and R7 represents a hydrogen atom, or optionally substituted lower alkyl), or —S(O)nR4 (wherein R4 has the same definition as described above, and n represents an integer of 0 to 2),
• R2A represents an optionally substituted cycloalkyl, optionally substituted aryl, an optionally substituted aromatic heterocyclic group, or an optionally substituted aliphatic heterocyclic group,
• QA represents a hydrogen atom, halogen, or optionally substituted lower alkyl,
• R3A represents (i) —C(═O)NHR9A, wherein R9A represents a hydrogen atom, optionally substituted lower alkyl, optionally substituted lower alkenyl, optionally substituted cycloalkyl, optionally substituted cycloalkenyl, optionally substituted aralkyl, optionally substituted aryl, an optionally substituted aromatic heterocyclic group, an optionally substituted aliphatic heterocyclic group, or —OR10 (wherein R10 represents optionally substituted lower alkyl, optionally substituted lower alkenyl, optionally substituted cycloalkyl, optionally substituted aralkyl, optionally substituted aryl, an optionally substituted aromatic heterocyclic group, or an optionally substituted aliphatic heterocyclic group), (ii) —C(═O)NR7A—NR7BC(═O)R10 (wherein R7A and R7B may be the same or different, and each has the same definition as the above R7, and R10 has the same definition as described above), (iii) —NHC(═O)R10 (wherein R10 has the same definition as described above), (iv) —NHC(═O)NR8AR9A (wherein R8A and R9A may be the same or different, and have the same definition as the above R9A), (v) —NR7AC(═O)OR10 (wherein R7A and R10 have the same definitions as described above, respectively), (vi) —SO2NR8AR9A (wherein R8A and R9A may be the same or different, and each has the same definition as the above R9A), (vii) —NHSO2R10 (wherein R10 has the same definition as described above), (viii) —NHSO2NR8AR9A (wherein R8A and R9A may be the same or different, and each has the same definition as the above R9A), or (ix) optionally substituted benzimidazol-2-yl,
• L1A represents —CR11AR11B— (wherein R11A and R11B may be the same or different, and each represents a hydrogen atom, optionally substituted lower alkyl, halogen, optionally substituted lower alkoxy, or hydroxy), or —(CR11AR11B)n1-L2- (wherein R11A and R11B may be the same or different, and each represents a hydrogen atom, optionally substituted lower alkyl, halogen, optionally substituted lower alkoxy, or hydroxy, n1 represents an integer of 0 to 1, and L2 represents —C(═O)—, —O—, —S(O)n2- (wherein n2 represents an integer of 0 to 1), or —SO2NR7C— (wherein R7C represents a hydrogen atom, optionally substituted lower alkyl, or optionally substituted cycloalkyl), and
• W1A and W2A may be the same or different, and each represents C—R12 (wherein R12 represents a hydrogen atom, halogen, optionally substituted lower alkyl, optionally substituted cycloalkyl, optionally substituted lower alkoxy, or optionally substituted lower alkenyl).