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US 9,000,125 B2Granted
Approach to treat intraocular hypertension
OwnerHans-Arne Hansson, Stefan Lange +1inventors
InventorsHans-Arne Hansson, Stefan Lange, Eva Jennische
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OwnerHans-Arne Hansson, Stefan Lange +1inventors
InventorsHans-Arne Hansson, Stefan Lange, Eva Jennische
Estimating the term…
The present invention relates to the use of antisecretory factors, such as antisecretory proteins, homologues, derivatives and/or fragments thereof having antisecretory activity, for the manufacture of a pharmaceutical composition for use in the treatment and/or prevention of intraocular hypertension. The invention thus relates to the use of pharmaceutical compositions comprising antisecretory factors in the treatment and/or prevention of intraocular hypertension, which is preferably characterized by hampered outflow of body fluid resulting in elevated pressure in the eye. The invention provides for a novel approach for treating and/or preventing such a condition turning the intraocular pressure to an acceptable level, optionally 21 mm Hg, or less.
A method of treating intraocular hypertension comprising administering to a subject in need of such treatment in an amount sufficient to decrease intraocular pressure a composition comprising an antisecretory factor (AF) protein of SEQ ID NO:6, or a fragment or homologue thereof comprising SEQ ID NO:4, and a pharmaceutically acceptable excipient.
Dependencies are inferred from the claim text.