# US 9,000,066 B2 · Multi-modal shape memory polymers > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 9,000,066 B2 - Document ID: US9000066B2 - Status: Granted - Kind: B2 - Application number: 12/595,341 - Filed: 2008-04-18 - Published: 2011-06-16 - Granted: 2015-04-07 - Earliest claimed: 2007-04-19 - Assignees: Smith & Nephew, Inc. - Applicants: Malcolm Brown; Horacio Montes De Oca Balderas; Michael Hall; John Rose - Inventors: Malcolm Brown; Horacio Montes De Oca Balderas; Michael Hall; John Rose - Web page: https://patentgrep.com/patent/US9000066B2 ## CPC - A61L 27/26: Mixtures of macromolecular compounds - A61F 2/28: Bones - A61L 27/50: Materials characterised by their function or physical properties {, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials} - A61L 27/54: Biologically active materials, e.g. therapeutic substances {(A61L27/227 takes precedence)} - A61L 27/56: Porous materials, {e.g. foams or sponges} - A61L 31/04: Macromolecular materials - A61L 31/14: Materials characterised by their function or physical properties {, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials} - C08L 33/08: Homopolymers or copolymers of acrylic acid esters - C08L 33/10: Homopolymers or copolymers of methacrylic acid esters - C08L 33/12: Homopolymers or copolymers of methyl methacrylate - C08L 35/06: Copolymers with vinyl aromatic monomers - C08L 67/04: Polyesters derived from hydroxycarboxylic acids, e.g. lactones (C08L67/06 takes precedence) - A61F 2002/2839: {Bone plugs or bone graft dowels} - A61L 2400/16: Materials with shape-memory or superelastic properties - C08G 2280/00: Compositions for creating shape memory - C08L 25/04: Homopolymers or copolymers of styrene - C08L 33/06: of esters containing only carbon, hydrogen and oxygen, which oxygen atoms are present only as part of the carboxyl radical - A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K) - A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C) - C08L: COMPOSITIONS OF MACROMOLECULAR COMPOUNDS (compositions based on polymerisable monomers C08F, C08G; artificial filaments or fibres D01F; textile treating compositions D06) - C08G: MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS ## Abstract The present disclosure relates to a multi-modal shape memory polymer material comprising a blend of at least one polymer component having a first molecular weight and at least a second polymer component having a second molecular weight that is less than the first component. ## Claims ### Claim 1 A bone implantation article comprising a multi-modal shape memory polymer material comprising a blend of at least a first polymer component having a first molecular weight and at least a second polymer component having a second molecular weight that is less than the first component, the first polymer component and the second polymer component are miscible, at least one of the first or second polymer components are non-resorbable, and wherein upon implanting the article into bone and providing the article with energy and heating to a temperature higher than the glass transition temperature of the polymer, but lower than its melting temperature, the material flows into pores of the bone thereby enhancing fixation of the article to bone. ### Claim 2 (depends on 1) The article of claim 1, wherein the first molecular weight is in excess of about 50,000 Daltons and the second molecular weight is up to about 20,000 Daltons. ### Claim 3 (depends on 1) The article of claim 1, wherein the first molecular weight is between about 50,000 and about 1,000,000 Daltons and the second molecular weight is between about 2,000 and about 20,000 Daltons. ### Claim 4 (depends on 1) The article of claim 1, wherein the first polymer component comprises about 80% of the polymer blend and the second polymer component comprises about 20% of the polymer blend. ### Claim 5 (depends on 2) The article of claim 2, wherein the first polymer component comprises about 80% of the polymer blend and the second polymer component comprises about 20% of the polymer blend. ### Claim 6 (depends on 1) The article of claim 1, wherein the first polymer component and the second polymer component are both non-resorbable. ### Claim 7 (depends on 1) The article of claim 1, wherein one of the first polymer component and the second polymer component is resorbable and one of the first polymer component and the second polymer component is non-resorbable. ### Claim 8 (depends on 1) The article of claim 1, wherein the material comprises reinforced polymeric material comprising a composite or matrix including reinforcing material or phases selected from the group consisting of glass fibers, carbon fibers, polymeric fibers, ceramic particualtes, rods, and platelets. ### Claim 9 (depends on 1) The article of claim 1, wherein the material is porous. ### Claim 10 (depends on 1) The article of claim 1, wherein the material comprises active agents selected from the group consisting of bone morphogenic proteins, antibiotics, anti-inflammatories, angiogenic factors, osteogenic factors, monobutyrin, thrombin, modified proteins, platelet rich plasma, platelet rich solution, platelet poor plasma, platelet poor solution, and bone marrow aspirate. ### Claim 11 (depends on 10) The article of claim 10, wherein the active agent is incorporated into the polymeric shape memory material to be released during the relaxation and/or degradation of the polymer material. ### Claim 12 (depends on 10) The article of claim 10, wherein the active agent combats infection and/or promotes new tissue growth at the site of implantation. ### Claim 13 (depends on 1) The article of claim 1, wherein at least one of the first or second polymer components is selected from the group consisting of polylyacrylate, polymethyl methacrylate polymer or copolymer thereof, polybutyl methacrylate polymer or copolymer thereof, and polystyrene copolymer.