US 9,000,039 B2Granted

Sn-1(3) monoacylglycerides and lipid absorption

AssigneeNestec S.A.

InventorsFrederic Destaillats, Cristina Cruz-Hernandez, Fabiola Dionisi, Isabelle Masserey-Elmelegy, Manuel Oliveira, Julie Moulin

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Abstract

The present invention relates generally to the field of lipids and in particular aims at improving lipid absorption, for example under conditions of lipid maldigestion or malabsorption. One embodiment of the present invention relates to a composition comprising sn-1(3) monoacylglycerols, wherein the sn-1 or sn-3 position is occupied by an acyl group such as a fatty acid and the sn-2 position remains unoccupied. The fatty acid may be one with anti-inflammatory properties.

Claims15

Dependent claims

A method for the treatment of inflammatory disorders, the method comprising administering to a subject suffering from a lipid maldigestion or malabsorption condition a composition comprising a sn-1(3)-monoacylglycerol, wherein the acyl group is a fatty acid having anti-inflammatory properties, the fatty acid selected from the group consisting of eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), α-linolenic acid (ALA), stearidonic acid, γ-linolenic acid (GLA), dihomo-γ-linolenic acid (DGLA), n-3 docosapentanenoic acid (DPA), sciadonic acid, juniperonic acid, and combinations thereof.

Dependencies are inferred from the claim text.

Facts

Application: 14/009,981Filed 3 Apr 2012
Priority: EP 111609294 Apr 2011
Published: US 2014/0031426 A130 Jan 2014
Granted: 7 Apr 2015
Term ends: Not estimatedThe source records don’t support an estimate.

Classification33 codes

A61K 31/232
Of acids having a carboxyl group bound to a chain of seven or more carbon atoms: having three or more double bonds, e.g. etretinate
A23L 33/12
Fatty acids or derivatives thereof; Fats or oils: fatty acids or derivatives thereof
A61K 31/23
Of acyclic acids, e.g. pravastatin: of acids having a carboxyl group bound to a chain of seven or more carbon atoms
A61K 31/231
Of acids having a carboxyl group bound to a chain of seven or more carbon atoms: having one or two double bonds

Family

US 2014/0031426 A1Pre-grant publication · published 30 Jan 2014
US 9,000,039 B2This patent

From the US filing history. Foreign family members aren’t listed.

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Abstract

Facts

Application

14/009,981Filed 3 Apr 2012

Priority

EP 111609294 Apr 2011

Published

US 2014/0031426 A130 Jan 2014

Granted

7 Apr 2015

Term ends

Not estimatedThe source records don’t support an estimate.

Classification33 codes

A61K 31/232
Of acids having a carboxyl group bound to a chain of seven or more carbon atoms: having three or more double bonds, e.g. etretinate
A23L 33/12
Fatty acids or derivatives thereof; Fats or oils: fatty acids or derivatives thereof
A61K 31/23
Of acyclic acids, e.g. pravastatin: of acids having a carboxyl group bound to a chain of seven or more carbon atoms
A61K 31/231
Of acids having a carboxyl group bound to a chain of seven or more carbon atoms: having one or two double bonds