Back to results
US 9,000,010 B2Granted
Alkyl-heterocycle carbamate derivatives, their preparation and their therapeutic application
AssigneeSanofi
InventorsAhmed Abouabdellah, Antoine Ravet
Life of this patent
Estimating the term…
Loading patent…
Loading patent…
AssigneeSanofi
InventorsAhmed Abouabdellah, Antoine Ravet
Estimating the term…
The invention relates to compounds corresponding to the general formula (I): in which R2 represents a hydrogen, fluorine, hydroxyl, cyano, trifluoromethyl, C1-6-alkyl, C1-6-alkoxy or —NR8R9; n and m represent, independently of one another, an integer equal to 1, 2 or 3, it being understood that the sum m+n is at most equal to 5; A represents a covalent bond, an oxygen, a C1-6-alkylene or —O—C1-6-alkylene; R1 represents a phenyl or a heterocycle which is optionally substituted; R3 represents a hydrogen, fluorine, C1-6-alkyl or trifluoromethyl; R4 represents an optionally substituted 5-membered heterocycle; in the form of the base or of an addition salt with an acid; with the exclusion of 5-methylisoxazol-3-ylmethyl 4-hydroxy-4-(4-chlorophenyl)piperidine-1-carboxylate. The invention also relates to a process for the preparation of the compounds of formula (I), to compositions comprising them and to their therapeutic application.
A compound according to the formula (I):
A compound chosen from the group consisting of:
Dependencies are inferred from the claim text.