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US 8,999,997 B2Granted
Chemical compounds
AssigneeAstraZeneca AB
InventorsKevin Foote, Johannes Wilhelmus Maria Nissink, Paul Turner
Life of this patent
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Abstract
There is provided pyrimidinyl compounds of Formula (I), wherein: R2 is or pharmaceutically acceptable salts thereof, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
Claims4
A method for treating breast cancer which comprises administering to a patient in need thereof a therapeutically effective amount of a compound of formula (I),
- wherein:
- R1 is 3-methylmorpholin-4-yl;
- R2 is
- R2C is hydrogen;
- R2D is hydrogen;
- R3 is methyl;
- R4 and R5 together with the atom to which they are attached form Ring A;
- Ring A is a cyclopropyl ring;
- and
- R6 is hydrogen,
- or a pharmaceutically acceptable salt thereof.
8 more elements
Dependencies are inferred from the claim text.