N-[(het)arylalkyl)] pyrazole(thio)carboxamides and their heterosubstituted analogues

A compound of formula (I)

• wherein
• X1 and X2 which can be the same or different, represent a halogen atom;
• Y represents a C1-C4-alkyl;
• T represents O or S;
• Q1 represents CR1R2;
• —CR3═CR4—;
• —CR3═N—O—;
• or —C(═W)—;
• Q2, Q3 and Q4, which can be the same or different, represent a direct bond;
• CR1R2;
• —CR3═CR4—;
• —C≡C—;
• —CR3═N—O—;
• —O—N═CR3—;
• O;
• S;
• SO;
• SO2;
• NR5;
• SiR6R7;
• or —C(═U)—;
• B represents a phenyl ring that can be substituted by up to 5 groups X which can be the same or different;
• a naphthyl ring that can be substituted by up to 7 groups X which can be the same or different;
• a saturated, partially saturated or unsaturated, monocyclic or fused bicyclic 4-, 5-, 6-, 7-, 8-, 9-, 10-membered ring comprising from 1 up to 4 heteroatoms selected in the list consisting of N, O, S, that can be substituted by up to 6 groups X which can be the same or different;
• a hydrogen atom;
• a halogen atom;
• a substituted or non-substituted C1-C12-alkyl group;
• a C1-C12-halogenoalkyl group having 1 to 9 halogen atoms that can be the same or different;
• a substituted or non-substituted C3-C8-cycloalkyl group;
• a substituted or non-substituted C3-C8-cycloalkenyl group, a bicyclo[2.2.1]heptan-2-yl group;
• a tri(C1-C8-alkyl)silyl group;
• a substituted or non-substituted C2-C12 alkenyl group;
• or a substituted or non-substituted C2-C12 alkynyl group;
• X represents a halogen atom;
• nitro;
• cyano;
• isonitrile;
• hydroxy;
• amino;
• sulfanyl;
• pentafluoro-λ6-sulfanyl;
• formyl;
• formyloxy;
• formylamino;
• substituted or non-substituted (hydroxyimino)-C1-C8-alkyl;
• substituted or non-substituted (C1-C8-alkoxyimino)-C1-C8-alkyl;
• substituted or non-substituted (C2-C8-alkenyloxyimino)-C1-C8-alkyl;
• substituted or non-substituted (C2-C8alkynyloxyimino)-C1-C8-alkyl;
• substituted or non-substituted (benzyloxyimino)-C1-C8-alkyl;
• carboxy;
• carbamoyl;
• N-hydroxycarbamoyl;
• carbamate;
• substituted or non-substituted C1-C8-alkyl;
• C1-C8-halogenoalkyl having 1 to 5 halogen atoms;
• substituted or non-substituted C2-C8-alkenyl;
• C2-C8-halogenoalkenyl having 1 to 5 halogen atoms;
• substituted or non-substituted C2-C8-alkynyl;
• C2-C8-halogenoalkynyl having 1 to 5 halogen atoms;
• substituted or non-substituted C1-C8-alkoxy;
• C1-C8-halogenoalkoxy having 1 to 5 halogen atoms;
• substituted or non-substituted C1-C8-alkylsulfanyl;
• C1-C8-halogenoalkylsulfanyl having 1 to 5 halogen atoms;
• substituted or non-substituted C1-C8-alkylsulfinyl;
• C1-C8-halogenoalkylsulfinyl having 1 to 5 halogen atoms;
• substituted or non-substituted C1-C8-alkylsulfonyl;
• C1-C8-halogenoalkylsulfonyl having 1 to 5 halogen atoms;
• substituted or non-substituted C1-C8-alkylamino;
• substituted or non-substituted di-C1-C8-alkylamino;
• substituted or non-substituted C2-C8-alkenyloxy;
• C2-C8-halogenoalkenyloxy having 1 to 5 halogen atoms;
• substituted or non-substituted C3-C8-alkynyloxy;
• C2-C8-halogenoalkynyloxy having 1 to 5 halogen atoms;
• substituted or non-substituted C3-C7-cycloalkyl;
• C3-C7-halogenocycloalkyl having 1 to 5 halogen atoms;
• substituted or non-substituted (C3-C7-cycloalkyl)-C1-C8-alkyl;
• substituted or non-substituted (C3-C7-cycloalkyl)-C2-C8-alkenyl;
• substituted or non-substituted (C3-C7-cycloalkyl)-C2-C8-alkynyl;
• substituted or non-substituted tri(C1-C8-alkyOsilyl;
• substituted or non-substituted tri(C1-C8-alkyl)silyl-C1-C8-alkyl;
• substituted or non-substituted C1-C8-alkylcarbonyl;
• C1-C8-halogenoalkylcarbonyl having 1 to 5 halogen atoms;
• substituted or non-substituted C1-C8-alkylcarbonyloxy;
• C1-C8-halogenoalkylcarbonyloxy having 1 to 5 halogen atoms;
• substituted or non-substituted C1-C8-alkylcarbonylamino;
• C1-C8-halogenoalkyl- carbonylamino having 1 to 5 halogen atoms;
• substituted or non-substituted C1-C8-alkoxycarbonyl;
• C1-C8-halogenoalkoxycarbonyl having 1 to 5 halogen atoms;
• substituted or non-substituted C1-C8-alkyloxycarbonyloxy;
• C1-C8-halogenoalkoxycarbonyloxy having 1 to 5 halogen atoms;
• substituted or non-substituted C1-C8-alkylcarbamoyl;
• substituted or non-substituted di-C1-C8alkylcarbamoyl;
• substituted or non-substituted C1-C8-alkylaminocarbonyloxy;
• substituted or non-substituted di-C1-C8-alkylaminocarbonyloxy;
• substituted or non-substituted N—(C1-C8-alkyl)hydroxy carbamoyl;
• substituted or non-substituted C1-C8-alkoxycarbamoyl;
• substituted or non-substituted N—(C1-C8-alkyl)-C1-C8-alkoxycarbamoyl;
• aryl that can be substituted by up to 6 groups Q which can be the same or different;
• arylalkyl that can be substituted by up to 6 groups Q which can be the same or different;
• C2-C8-arylalkenyl that can be substituted by up to 6 groups Q which can be the same or different;
• C2-C8-arylalkynyl that can be substituted by up to 6 groups Q which can be the same or different;
• aryloxy that can be substituted by up to 6 groups Q which can be the same or different;
• arylsulfanyl that can be substituted by up to 6 groups Q which can be the same or different;
• arylamino that can be substituted by up to 6 groups Q which can be the same or different;
• C1-C8-arylalkyloxy that can be substituted by up to 6 groups Q which can be the same or different;
• C1-C8-arylalkylsulfanyl that can be substituted by up to 6 groups Q which can be the same or different;
• or C1-C8-arylalkylamino that can be substituted by up to 6 groups Q which can be the same or different;
• or
• two substituent X together with the consecutive carbon atoms to which they are linked can form a 5- or 6-membered, saturated carbocycle or saturated heterocycle, which can be substituted by up to four groups Q which can be the same or different;
• Z1 represents a hydrogen atom;
• a formyl group;
• a substituted or non-substituted C1-C8-alkyl;
• a substituted or non substituted C1-C8-alkoxy;
• a non-substituted C3-C7-cycloalkyl or a C3-C7-cycloalkyl substituted by up to 10 atoms or groups that can be the same or different and that can be selected in the list consisting of halogen atoms, cyano, C1-C8-alkyl, C1-C8-halogenoalkyl comprising up to 9 halogen atoms that can be the same or different, C1-C8-alkoxy, C1-C8-halogenoalkoxy comprising up to 9 halogen atoms that can be the same or different, C1-C8-alkoxycarbonyl, C1-C8-halogenoalkoxycarbonyl comprising up to 9 halogen atoms that can be the same or different, C1-C8-alkylaminocarbonyl and di-C1-C8-alkylaminocarbonyl;
• R1 and R2 independently represent a hydrogen atom;
• a halogen atom;
• cyano;
• substituted or non-substituted C1-C12-alkyl;
• substituted or non-substituted C2-C12-alkenyl;
• substituted or non-substituted C2-C12-alkynyl;
• substituted or non-substituted C3-C7-cycloalkyl;
• C1-C12-halogenoalkyl having 1 to 5 halogen atoms;
• substituted or non-substituted C1-C8-alkoxy;
• substituted or non-substituted C1-C8-alkylsulfanyl;
• substituted or non-substituted C1-C8-alkylamino;
• substituted or non-substituted di-(C1-C8-alkyl)amino;
• or substituted or non-substituted C1-C8-alkoxycarbonyl;
• or R1 and R2 are a C2-C5-alkylene group that can be substituted by up to four groups that can be the same or different and that can be selected in the list consisting of halogen atoms, C1-C8-alkyl or C1-C2-halogenoalkyl comprising up to 5 halogen atoms that can be the same or different;
• or
• The R1 substituent of the group Qi and the R1 substituent of the group Qi+1, i being an integer between 1 and 3, together with the consecutive carbon atoms to which they are linked can form a 3-, 4-, 5-, -6 or 7-membered saturated carbocycle that can be substituted by up to four groups that can be the same or different and that can be selected in the list consisting of halogen atoms, C1-C8-alkyl or C1-C2-halogenoalkyl comprising up to 5 halogen atoms that can be the same or different;
• or
• The R1 substituent of the group Qi and the R1 substituent of the group Qi+2, i being an integer between 1 and 2, together with the consecutive carbon atoms to which they are linked can form a 3-, 4-, 5-, 6- or 7-membered saturated carbocycle that can be substituted by up to four groups that can be the same or different and that can be selected in the list consisting of halogen atoms, C1-C8-alkyl or C1-C2-halogenoalkyl comprising up to 5 halogen atoms that can be the same or different;
• R3 and R4 independently represent a hydrogen atom;
• substituted or non-substituted C1-C8-alkyl;
• substituted or non-substituted C2-C8-alkenyl;
• substituted or non-substituted C2-C8-alkynyl;
• substituted or non-substituted C3-C7-cycloalkyl;
• or C1-C8-halogenoalkyl having 1 to 5 halogen atoms;
• R5 represents a hydrogen atom;
• a substituted or non-substituted C1-C8-alkyl;
• a C1-C8-halogenoalkyl comprising up to 9 halogen atoms that can be the same or different;
• a substituted or non-substituted C2-C8-alkenyl;
• a C2-C8-halogenoalkenyl comprising up to 9 halogen atoms that can be the same or different;
• a substituted or non-substituted C3-C8-alkynyl;
• a C3-C8-halogenoalkynyl comprising up to 9 halogen atoms that can be the same or different;
• a substituted or non-substituted C3-C7-cycloalkyl;
• a C3-C7-halogeno-cycloalkyl comprising up to 9 halogen atoms that can be the same or different;
• a substituted or non-substituted C3-C7-cycloalkyl-C1-C8-alkyl;
• formyl;
• a substituted or non-substituted C1-C8-alkylcarbonyl;
• C1-C8-halogenoalkylcarbonyl comprising up to 9 halogen atoms that can be the same or different;
• a substituted or non-substituted C1-C8-alkoxycarbonyl;
• C1-C8-halogenoalkoxycarbonyl comprising up to 9 halogen atoms that can be the same or different;
• a substituted or non-substituted C1-C8-alkylsulphonyl;
• C1-C8-halogenoalkylsulphonyl comprising up to 9 halogen atoms that can be the same or different;
• phenylmethylene that can be substituted by up to 7 groups Q which can be the same or different;
• or phenylsulphonyl that can be substituted by up to 5 groups Q which can be the same or different;
• R6 and R7 independently represent a substituted or non-substituted C1-C8-alkyl;
• W represents O;
• or S;
• U represents O;
• S;
• N—ORa;
• or N—CN;
• Ra represents a hydrogen atom;
• a substituted or non-substituted C1-C4-alkyl;
• or a C1-C4-halogenoalkyl comprising up to 7 halogen atoms that can be the same or different;
• Q independently represents a halogen atom;
• cyano;
• nitro;
• substituted or non-substituted C1-C8-alkyl;
• C1-C8-halogenoalkyl having 1 to 9 halogen atoms that can be the same or different;
• substituted or non-substituted C1-C8-alkoxy;
• C1-C8-halogenoalkoxy having 1 to 9 halogen atoms that can be the same or different;
• substituted or non-substituted C1-C8-alkylsulfanyl;
• C1-C8-halogenoalkylsulfanyl having 1 to 9 halogen atoms that can be the same or different;
• substituted or non-substituted tri(C1-C8)alkylsilyl;
• substituted or non-substituted tri(C1-C8)alkylsilyl-C1-C8-alkyl;
• substituted or non-substituted (C1-C8-alkoxyimino)-C1-C8-alkyl;
• substituted or non-substituted (benzyloxyimino)-C1-C8-alkyl;
• with the proviso that -Q1-Q2-Q3-Q4- does not represent CR1R2 when B represents a substituted or non-substituted phenyl, naphthyl or 2-pyridyl ring;
• or that -Q1-Q2-Q3-Q4- does not represent [CR1R2]2 or CR1R2—C(═W)— or a cycloalkyl-1,2-diyl group, when B represents a substituted or non-substituted phenyl, naphthyl or heterocyclic ring;
• or that Z1 does not represent a hydrogen atom when -Q1-Q2- represents a unsubstituted cyclohexyl-1,2-diyl group and -Q3-Q4- represents a substituted or non-substituted cyclopropyl-1,2-diyl group;
• as well as its salts, N-oxides, and optically active isomers.