Bis(fluoroalkyl)-1,4-benzodiazepinone compounds and prodrugs thereof

A compound of Formula (I):

• and/or at least one salt thereof, wherein:
• R1 is —CH2CH2CF3;
• R2 is —CH2CH2CF3 or —CH2CH2CH2CF3;
• R3 is H, —CH3, or Rx;
• R4 is H or Ry;
• Rx is:
• —CH2OC(O)CH(CH3)NH2, —CH2OC(O)CH(NH2)CH(CH3)2,
• —CH2OC(O)CH((CH(CH3)2)NHC(O)CH(NH2)CH(CH3)2,
• Ry is:
• —SCH2CH(NH2)C(O)OH, —SCH2CH(NH2)C(O)OCH3, or —SCH2CH(NH2)C(O)OC(CH3)3;
• Ring A is phenyl or pyridinyl;
• each Ra is independently Cl, C1-3 alkyl, —CH2OH, —CF3, cyclopropyl, —OCH3, and/or —O(cyclopropyl);
• each Rb is independently F, Cl, —CH3, —CH2OH, —CF3, cyclopropyl, and/or —OCH3;
• y is zero, 1, or 2;
• and
• z is zero, 1, or 2;
• provided that if R3 is Rx then R4 is H;
• and
• provided that if R4 is Ry then R3 is H or —CH3.