Substituted ketonic isoxazoline compounds and derivatives for combating animal pests

A compound of formula (I-A)

• wherein
• Y is hydrogen or halogen;
• p is 0, 1, 2, 3 or 4;
• m is 0 or 1;
• G is selected from the group consisting of hydrogen, nitro, cyano, —SCN, C1-C6-alkyl, C1-C6-haloalkyl, C1-C6-alkoxy, C1-C6-haloalkoxy, C1-C6-alkylthio, C1-C6-haloalkylthio, C3-C8-cycloalkyl, C3-C8-halocycloalkyl, C2-C6-alkenyl, C2-C6-haloalkenyl, C2-C6-alkynyl, C2-C6 haloalkynyl, wherein the carbon atoms of the aforementioned aliphatic and cyclo-aliphatic radicals may optionally be substituted with one or more R6, which are independently selected from one another;
• NR9aR9b, S(O)nR7, —S(O)nNR9aR9b, C(═O)R6, C(═O)OR7, C(═O)NR9aR9b, C(═S)R6, C(═S)SR7, C(═S)NR9aR9b, C(═NR8)R6;
• phenyl, optionally substituted with one or more substituents R10, which are selected independently from one another, and a 3-, 4-, 5-, 6- or 7-membered saturated, partly saturated or unsaturated aromatic heterocyclic ring comprising 1, 2 or 3 heteroatoms selected from the group consisting of oxygen, nitrogen and sulfur, optionally substituted with k substituents R10, selected independently from one another, and wherein the nitrogen and/or the sulfur atom(s) of the heterocyclic ring may optionally be oxidized;
• R1, R2 are selected independent from one another from the group consisting of halogen, cyano, azido, nitro, —SCN, SF5, C1-C6-alkyl, C1-C6-haloalkyl, C1-C6-alkoxy, C1-C6-haloalkoxy, C1-C6-alkylthio, C1-C6-alkylsulfinyl, C1-C6-alkylsulfonyl, C1-C6-haloalkylthio, C3-C8-cycloalkyl, C3-C8-halocycloalkyl, C2-C6-alkenyl, C2-C6-haloalkenyl, C2-C6-alkynyl, C2-C6 haloalkynyl, wherein the carbon atoms of the aforementioned aliphatic and cyclo-aliphatic radicals may optionally be substituted with one or more R6, which are independently selected from one another;
• Si(R11)2R12, OR7, OSO2R7, S(O)nR7, S(O)nNR9aR9b, NR9aR9b, C(═O)NR9aR9b, C(═S)NR9aR9b, C(═O)OR7,
• phenyl, optionally substituted with one or more substituents R10, which are independently selected from one another;
• and
• a 2-, 4-, 5-, 6- or 7-membered saturated, partly saturated or unsaturated aromatic heterocyclic ring comprising 1, 2 or 3 heteroatoms selected from the group consisting of oxygen, nitrogen and sulfur, optionally substituted with k substituents R10, selected independently from one another, and wherein the nitrogen and/or the sulfur atom(s) of the heterocyclic ring may optionally be oxidized,
• or,
• R1 and R2 may together form ═CR13R14;
• ═CR13NR17aR17b, ═S(O)nR16;
• ═S(O)nNR17aR17b, ═NR17a;
• ═NOR16;
• ═NNR17a;
• or
• R1 and R2 may form together with the carbon atoms to which R1 and R2 are bonded to a 3-, 4-, 5-, 6-, 7- or 8-membered saturated, partly or fully unsaturated or aromatic carbocyclic or heterocyclic ring optionally comprising 1, 2 or 3 heteroatoms selected from the group consisting of oxygen, nitrogen and sulfur and/or optionally substituted with k substituents R10, selected independently from one another, and wherein the nitrogen and/or the sulfur atom(s) of the heterocyclic ring may optionally be oxidized;
• R4 is attached to a carbon atom of the ring and is selected, independently from each other if p>1, from the group consisting of hydrogen, halogen, cyano, azido, nitro, —SCN, SF5, C1-C6-alkyl, C3-C8-cycloalkyl, C2-C6-alkenyl, C2-C6-alkynyl, wherein the carbon atoms of the aforementioned aliphatic and cyclo-aliphatic radicals may optionally be substituted with one or more R6, which are independently selected from one another;
• Si(R11)2R12, OR7, —OS(O)nR7, S(O)nR7, NR9aR9b, N(R9a)C(═O)R6, C(═O)R6, —C(═O)OR7, C(═NR8)R6, C(═S)R6,
• phenyl, optionally substituted with one or more substituents independently selected from R10, which are selected independently from one another;
• and
• a 3-, 4-, 5-, 6- or 7-membered saturated, partly saturated or unsaturated aromatic heterocyclic ring comprising 1, 2 or 3 heteroatoms selected from the group consisting of oxygen, nitrogen and sulfur, optionally substituted with k substituents R10, independently selected from one another, and wherein the nitrogen and/or the sulfur atom(s) of the heterocyclic ring may optionally be oxidized,
• or,
• when p is 2 or more and two of R4 are adjacent,
• the two adjacent R4 may form a bridge selected from the group consisting of CH2CH2CH2CH2, CH═CH—CH═CH, N═CH—CH═CH, CH═N—CH═CH, N═CH—N═CH, OCH2CH2CH2, OCH═CHCH2, CH2OCH2CH2, OCH2CH2O, OCH2OCH2, CH2CH2CH2, CH═CHCH2, CH2CH2O, CH═CHO, CH2OCH2, CH2C(═O)O, C(═O)OCH2, O(CH2)O, SCH2CH2CH2, SCH═CHCH2, CH2SCH2CH2, SCH2CH2S, SCH2SCH2, CH2CH2S, CH═CHS, CH2SCH2, CH2C(═S)S, C(═S)SCH2, S(CH2)S, CH2CH2NR9a, CH2CH═N, OCH═N, SCH═N, and CH═CH—NR9a, wherein the carbon atoms of the bridge may optionally be substituted with one or two substituents selected from the group consisting of ═O, OH, CH3, OCH3, halogen, halomethyl or halomethoxy;
• R5 is selected from the group consisting of hydrogen, halogen, cyano, azido, nitro, —SCN, SF5, C1-C6-alkyl, C1-C6-haloalkyl, C1-C6-alkoxy, C1-C6-haloalkoxy, C1-C6-alkylthio, C1-C6-alkylsulfinyl, C1-C6-alkylsulfonyl, C1-C6-haloalkylthio, C3-C8-cycloalkyl, C3-C8-halocycloalkyl, C2-C6-alkenyl, C2-C6-haloalkenyl, C2-C6-alkynyl, C2-C6 haloalkynyl, Si(R11)2R12, OR16, OSO2R16, S(O)nR16, S(O)nNR17aR17b, NR17aR17b, NR17aC(═O)R16C(═O)NR17aR17b, C(═S)NR17aR17b, C(═O)OR16,
• phenyl, optionally substituted with one or more substituents R10, which are independently selected from one another;
• and
• a 3-, 4-, 5-, 6- or 7-membered saturated, partly saturated or unsaturated aromatic heterocyclic ring comprising 1, 2 or 3 heteroatoms selected from the group consisting of oxygen, nitrogen and sulfur, optionally substituted with k substituents R10, selected independently from one another, and wherein the nitrogen and/or the sulfur atom(s) of the heterocyclic ring may optionally be oxidized;
• or
• two R6 present on one carbon atom may together form ═O, ═CR13R14;
• ═S(O)nR16;
• ═S(O)nNR17aR17b, ═NR17a, ═NOR16;
• ═NNR17aR17b;
• or
• two R6 may form a 3-, 4-, 5-, 6-, 7- or 8-membered saturated or partly unsaturated carbocyclic or heterocyclic ring together with the carbon atoms to which the two R6 are bonded to;
• R7 is, independent from each other, selected from the group consisting of hydrogen, cyano, C1-C6-alkyl, C1-C6-haloalkyl, C1-C6-alkoxy, C1-C6-haloalkoxy, C1-C6-alkylthio, C1-C6-alkylsulfinyl, C1-C6-alkylsulfonyl, C1-C6-haloalkylthio, C3-C8-cycloalkyl, C4-C8-alkylcycloalkyl, C3-C8-halocycloalkyl, C2-C6-alkenyl, C2-C6-haloalkenyl, C2-C6-alkynyl, C2-C6 haloalkynyl, —Si(R11)2R12, S(O)nR16, —S(O)nNR17aR17b, NR17aR17b, —N═CR13R14, —C(═O)R16, C(═O)NR17aR17b, C(═S)NR17aR17b, C(═O)OR16,
• phenyl, optionally substituted with one or more substituents R18;
• which are selected independently from one another;
• a 3-, 4-, 5-, 6- or 7-membered saturated, partly saturated or unsaturated aromatic heterocyclic ring comprising 1, 2 or 3 heteroatoms selected from the group consisting of oxygen, nitrogen and sulfur, optionally substituted with k substituents R18, selected independently from one another, and wherein the nitrogen and/or the sulfur atom(s) of the heterocyclic ring may optionally be oxidized;
• R8 is selected from the group consisting of hydrogen, nitro, cyano, C1-C10-alkyl, C3-C8-cycloalkyl, C2-C10-alkenyl, C2-C10-alkynyl, wherein the carbon atoms of the aforementioned aliphatic and cyclo-aliphatic radicals may optionally be substituted with one or more R15, which are selected independently from one another;
• NR17aR17b, Si(R11)2R12, OR16, S(O)nR16, S(O)nNR17aR17b, C(═O)R15, —C(═O)OR16, C(═O)NR17aR17b, C(═S)R15, C(═S)SR16, C(═S)NR17aR17b;
• C(═NR17a)R15;
• phenyl, optionally substituted with one or more substituents R18, which are selected independently from one another;
• and
• a 3-, 4-, 5-, 6- or 7-membered saturated, partly saturated or unsaturated aromatic heterocyclic ring comprising 1, 2 or 3 heteroatoms selected from the group consisting of oxygen, nitrogen and sulfur, optionally substituted with k substituents R18, independently selected from one another, and wherein the nitrogen and/or the sulfur atom(s) of the heterocyclic ring may optionally be oxidized;
• R9a, R9b are selected independent from one another from the group consisting of hydrogen, C1-C6-alkyl, optionally substituted with one or more substituents R10;
• C1-C6-haloalkyl, C1-C6-alkoxy, C1-C6-haloalkoxy, C1-C6-alkylthio, C1-C6-haloalkylthio, C3-C8-cycloalkyl, C3-C8-halocycloalkyl, C2-C6-alkenyl, C2-C6-haloalkenyl, C2-C6-alkynyl, C2-C6 haloalkynyl,
• S(O)nR16, —S(O)nNR17aR17b, C(═O)R15, C(═O)OR16, C(═O)NR17aR17b, C(═S)R15, C(═S)SR16, C(═S)NR17aR17b, C(═NR17a)R15,
• phenyl, optionally substituted with one or more substituents R18, which are selected independently from one another;
• a 3-, 4-, 5-, 6- or 7-membered saturated, partly saturated or unsaturated aromatic heterocyclic ring comprising 1, 2 or 3 heteroatoms selected from oxygen, nitrogen and/or sulfur, optionally substituted with k substituents R18, selected independently from one another, and wherein the nitrogen and/or the sulfur atom(s) of the heterocyclic ring may optionally be oxidized;
• or,
• R9a and R9b are together a C2-C7 alkylene chain and form a 3-, 4-, 5-, 6-, 7- or 8-membered saturated, partly saturated or unsaturated aromatic ring together with the nitrogen atom they are bonded to, wherein the alkylene chain may contain one or two heteroatoms selected from the group consisting of oxygen, sulfur and nitrogen, and may optionally be substituted with halogen, C1-C6-alkyl, C1-C6-haloalkyl, C1-C6-alkoxy, C1-C6-haloalkoxy, C1-C6-alkylthio, C1-C6-haloalkylthio, C3-C8-cycloalkyl, C3-C8-halocycloalkyl, C2-C6-alkenyl, C2-C6-haloalkenyl, C2-C6-alkynyl, C2-C6 haloalkynyl;
• phenyl, optionally substituted with one or more substituents R18;
• which are selected independently from one another;
• or
• a 3-, 4-, 5-, 6-, or 7-membered saturated, partly saturated or unsaturated aromatic heterocyclic ring comprising 1, 2 or 3 heteroatoms selected from the group consisting of oxygen, nitrogen and sulfur, optionally substituted with k substituents R18, selected independently from one another, and wherein the nitrogen and/or the sulfur atom(s) of the heterocyclic ring may optionally be oxidized;
• R10 is selected from the group consisting of hydrogen, halogen, cyano, azido, nitro, SCN, SF5, C1-C10-alkyl, C3-C8-cycloalkyl, C2-C10-alkenyl, C2-C10-alkynyl, wherein the carbon atoms of the aforementioned aliphatic and cyclo-aliphatic radicals may optionally be substituted with one or more R15, which are selected independently from one another;
• Si(R11)2R12, OR16, OS(O)nR16, —S(O)nR16, S(O)nNR17aR17b, NR17aR17b, C(═O)R15, C(═O)OR16, —C(═NR17a)R15, C(═O)NR17aR17b, C(═S)NR17aR17b,
• phenyl, optionally substituted with halogen, cyano, nitro, C1-C6-alkyl, C1-C6-haloalkyl, C1-C6-alkoxy or C1-C6-haloalkoxy;
• and
• a 3-, 4-, 5-, 6- or 7-membered saturated, partly saturated or unsaturated aromatic heterocyclic ring comprising 1, 2 or 3 heteroatoms selected from the group consisting of oxygen, nitrogen and sulfur, optionally substituted with k substituents selected independently from one another from the group consisting of halogen, cyano, NO2, C1-C6-alkyl, C1-C6-haloalkyl, C1-C6-alkoxy and C1-C6-haloalkoxy, and wherein the nitrogen and/or the sulfur atom(s) of the heterocyclic ring may optionally be oxidized;
• or
• two R10 present together on one atom of a partly saturated heterocyclic may be ═O, ═CR13R14;
• ═S(O)nR16;
• ═S(O)nNR17aR17b, ═NR17a, ═NOR16;
• or ═NNR17a;
• or,
• two R10 on adjacent carbon atoms may be a bridge selected from the group consisting of CH2CH2CH2CH2, CH═CH—CH═CH, N═CH—CH═CH, CH═N—CH═CH, N═CH—N═CH, OCH2CH2CH2, OCH═CHCH2, CH2OCH2CH2, OCH2CH2O, OCH2OCH2, CH2CH2CH2, CH═CHCH2, CH2CH2O, CH═CHO, CH2OCH2, CH2C(═O)O, C(═O)OCH2, O(CH2)O, SCH2CH2CH2, SCH═CHCH2, CH2SCH2CH2, SCH2CH2S, SCH2SCH2, CH2CH2S, CH—CHS, CH2SCH2, CH2C(═S)S, C(═S)SCH2, S(CH2)S, CH2CH2NR9a, CH2CH═N, CH═CH—NR9a, OCH═N, and SCH═N and form together with the carbon atoms to which the two R10 are bonded to a 5-membered or 6-membered partly saturated or unsaturated, aromatic carbocyclic or heterocyclic ring, wherein the ring may optionally be substituted with one or two substituents selected from the group consisting of ═O, OH, CH3, OCH3, halogen, halomethyl and halomethoxy;
• R11, R12 are selected independent from one another from the group consisting of hydrogen, halogen, C1-C6 alkyl, C1-C6 haloalkyl, C1-C6 alkoxyalkyl, C2-C6 alkenyl, C2-C6 haloalkenyl, C2-C6 alkynyl, C2-C6 haloalkynyl, C3-C8 cycloalkyl, C3-C8 halocycloalkyl, C1-C6 alkoxyalkyl, C1-C6 haloalkoxyalkyl, phenyl, optionally substituted with one or more substituents R18;
• which are selected independently from one another;
• and
• a 3-, 4-, 5-, 6- to 7-membered saturated, partly saturated or unsaturated aromatic heterocyclic ring comprising 1, 2 or 3 heteroatoms selected from the group consisting of oxygen, nitrogen and sulfur, optionally substituted with k substituents R18, selected independently from one another, and wherein the nitrogen and/or the sulfur atom(s) of the heterocyclic ring may optionally be oxidized;
• R13, R14 are selected independent from one another from the group consisting of hydrogen, C1-C4 alkyl, C1-C6 cycloalkyl, C1-C4 alkoxyalkyl, phenyl and benzyl;
• R15 is selected from the group consisting of hydrogen, halogen, cyano, azido, nitro, OH, SH, SCN, SF5, C1-C6-alkoxy, C1-C6-haloalkoxy, C1-C6-alkylthio, C1-C6-alkylsulfinyl, C1-C6-alkylsulfonyl, C1-C6-haloalkylthio, trimethylsilyl, triethylsilyl, tertbutyldimethylsilyl, (C1-C6-alkyl)amino or di-(C1-C6-alkyl)amino, (C1-C6-haloalkyl)amino, di-(C1-C6-haloalkyl)amino, C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C3-C8-cycloalkyl, wherein the four last mentioned aliphatic and cyclo-aliphatic radicals may be unsubstituted, partially or fully halogenated and/or oxygenated and/or may carry 1 or 2 radicals selected from C1-C4 alkoxy;
• phenyl, benzyl, pyridyl, and phenoxy, wherein the last four radicals may be unsubstituted, partially or fully halogenated and/or to carry 1, 2 or 3 substituents selected from the group consisting of C1-C6-alkyl, C1-C6-haloalkyl, C1-C6-alkoxy, C1-C6 haloalkoxy, (C1-C6-alkoxy)carbonyl, (C1-C6-alkyl)amino and di-(C1-C6-alkyl)amino;
• or
• two R15 present on the same carbon atom may together be ═O, ═CH(C1-C4-alkyl), ═C(C1-C4-alkyl)C1-C4-alkyl, ═N(C1-C6-alkyl) or ═NO(C1-C6-alkyl);
• R16 is selected from the group consisting of hydrogen, cyano, C1-C6-alkoxy, C1-C6-haloalkoxy, C1-C6-alkylthio, C1-C6-alkylsulfinyl, C1-C6-alkylsulfonyl, C1-C6-haloalkylthio, trimethylsilyl, triethylsilyl, tertbutyldimethylsilyl, C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C3-C8-cycloalkyl, wherein the four last mentioned radicals may be unsubstituted, partially or fully halogenated and/or oxygenated and/or may carry 1 or 2 radicals selected from C1-C4 alkoxy cyclopropyl, halocyclopropyl;
• phenyl, benzyl, pyridyl, and phenoxy, wherein the last four radicals may be unsubstituted, partially or fully halogenated and/or carry 1, 2 or 3 substituents selected from the group consisting of C1-C6-alkyl, C1-C6-haloalkyl, C1-C6-alkoxy, C1-C6 haloalkoxy and (C1-C6-alkoxy)carbonyl;
• R17a, R17b is selected from the group consisting of hydrogen, cyano, C1-C6-alkoxy, C1-C6-haloalkoxy, C1-C6-alkylthio, C1-C6-alkylsulfinyl, C1-C6-alkylsulfonyl, C1-C6-haloalkylthio, trimethylsilyl, triethylsilyl, tertbutyldimethylsilyl, C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C3-C8-cycloalkyl, wherein the four last mentioned aliphatic and cyclo-aliphatic radicals may be unsubstituted, partially or fully halogenated and/or oxygenated and/or may carry 1 or 2 radicals selected from C1-C4-alkoxy, C1-C4-alkyl, cyclopropyl, halocyclopropyl, pyridyl;
• phenyl, benzyl, pyridyl, and phenoxy, wherein the four last mentioned radicals may be unsubstituted, partially or fully halogenated and/or carry 1, 2 or 3 substituents selected from the group consisting of C1-C6-alkyl, C1-C6-haloalkyl, C1-C6-alkoxy, C1-C6 haloalkoxy and (C1-C6-alkoxy)carbonyl;
• or,
• R17a and R17b may together be a C2-C6 alkylene chain forming a 3- to 7-membered saturated, partly saturated or unsaturated ring together with the nitrogen atom R17a and R17b are bonded to, wherein the alkylene chain may contain 1 or 2 heteroatoms selected from the group consisting of oxygen, sulfur and nitrogen, and may optionally be substituted with halogen, C1-C4-haloalkyl, C1-C4-alkoxy or C1-C4-haloalkoxy, and wherein the nitrogen and/or the sulfur atom(s) of the heterocyclic ring may optionally be oxidized;
• R18 is selected from the group consisting of hydrogen, cyano, C1-C6-alkoxy, C1-C6-haloalkoxy, C1-C6-alkylthio, C1-C6-alkylsulfinyl, C1-C6-alkylsulfonyl, C1-C6-haloalkylthio, trimethylsilyl, triethylsilyl, tertbutyldimethylsilyl, C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C3-C8-cycloalkyl, wherein the four last mentioned aliphatic and cyclo-aliphatic radicals may be unsubstituted, partially or fully halogenated and/or oxygenated and/or may carry 1 or 2 radicals selected from C1-C4-alkoxy;
• phenyl, benzyl, pyridyl, and phenoxy, wherein the four last mentioned radicals may be unsubstituted, partially or fully halogenated and/or carry 1, 2 or 3 substituents selected from C1-C6-alkyl, C1-C6-haloalkyl, C1-C6-alkoxy, C1-C6 haloalkoxy), (C1-C6-alkoxy)carbonyl;
• or
• two R18 present together on one atom of a partly saturated atom may be ═O, ═N(C1-C6-alkyl), ═NO(C1-C6-alkyl), ═CH(C1-C4-alkyl) or ═C(C1-C4-alkyl)C1-C4-alkyl;
• or,
• two R18 on two adjacent carbon atoms may be together a C2-C6 alkylene chain, which form together with the carbon atom they are bonded to a 3-, 4-, 5-, 6- or 7-membered saturated, partly saturated or unsaturated aromatic, wherein the alkylene chain may contain 1 or 2 heteroatoms selected from the group consisting of oxygen, sulfur and nitrogen, and may optionally be substituted with halogen, C1-C4-haloalkyl, C1-C4-alkoxy or C1-C4-haloalkoxy, and wherein the nitrogen and/or the sulfur atom(s) of the heterocyclic ring may optionally be oxidized;
• n is 0, 1 or 2;
• and
• k is an integer selected from 0 to 10.

A compound of formula (I-B)

• wherein
• Y is hydrogen or halogen;
• and wherein
• p is 0, 1, 2, 3 or 4;
• m is 0 or 1;
• G is selected from the group consisting of hydrogen, nitro, cyano, —SCN, C1-C6-alkyl, C1-C6-haloalkyl, C1-C6-alkoxy, C1-C6-haloalkoxy, C1-C6-alkylthio, C1-C6-haloalkylthio, C3-C8-cycloalkyl, C3-C8-halocycloalkyl, C2-C6-alkenyl, C2-C6-haloalkenyl, C2-C6-alkynyl, C2-C6 haloalkynyl, wherein the carbon atoms of the aforementioned aliphatic and cyclo-aliphatic radicals may optionally be substituted with one or more R6, which are independently selected from one another;
• NR9aR9b, S(O)nR7, —S(O)nNR9aR9b, C(═O)R6, C(═O)OR7, C(═O)NR9aR9b, C(═S)R6, C(═S)SR7, C(═S)NR9aR9b, C(═NR8)R6;
• phenyl, optionally substituted with one or more substituents R10, which are selected independently from one another, and a 3-, 4-, 5-, 6- or 7-membered saturated, partly saturated or unsaturated aromatic heterocyclic ring comprising 1, 2 or 3 heteroatoms selected from the group consisting of oxygen, nitrogen and sulfur, optionally substituted with k substituents R10, selected independently from one another, and wherein the nitrogen and/or the sulfur atom(s) of the heterocyclic ring may optionally be oxidized;
• R1, R2 are selected independent from one another from the group consisting of halogen, cyano, azido, nitro, —SCN, SF5, C1-C6-alkyl, C1-C6-haloalkyl, C1-C6-alkoxy, C1-C6-haloalkoxy, C1-C6-alkylthio, C1-C6-alkylsulfinyl, C1-C6-alkylsulfonyl, C1-C6-haloalkylthio, C3-C8-cycloalkyl, C3-C8-halocycloalkyl, C2-C6-alkenyl, C2-C6-haloalkenyl, C2-C6-alkynyl, C2-C6 haloalkynyl, wherein the carbon atoms of the aforementioned aliphatic and cyclo-aliphatic radicals may optionally be substituted with one or more R6, which are independently selected from one another;
• Si(R11)2R12, OR7, OSO2R7, S(O)nR7, S(O)nNR9aR9b, NR9aR9b, C(═O)NR9aR9b, C(═S)NR9aR9b, C(═O)OR7,
• phenyl, optionally substituted with one or more substituents R10, which are independently selected from one another;
• and
• a 2-, 4-, 5-, 6- or 7-membered saturated, partly saturated or unsaturated aromatic heterocyclic ring comprising 1, 2 or 3 heteroatoms selected from the group consisting of oxygen, nitrogen and sulfur, optionally substituted with k substituents R10, selected independently from one another, and wherein the nitrogen and/or the sulfur atom(s) of the heterocyclic ring may optionally be oxidized,
• or
• R1 and R2 may together form ═CR13R14;
• ═CR13NR17aR17b, ═S(O)nR16;
• ═S(O)nNR17aR17b, ═NR17a;
• ═NOR16;
• ═NNR17a;
• or
• R1 and R2 may form together with the carbon atoms to which R1 and R2 are bonded to a 3-, 4-, 5-, 6-, 7- or 8-membered saturated, partly or fully unsaturated or aromatic carbocyclic or heterocyclic ring optionally comprising 1, 2 or 3 heteroatoms selected from the group consisting of oxygen, nitrogen and sulfur and/or optionally substituted with k substituents R10, selected independently from one another, and wherein the nitrogen and/or the sulfur atom(s) of the heterocyclic ring may optionally be oxidized;
• and
• R4 is attached to a carbon atom of the ring and is selected, independently from each other if p>1, from the group consisting of hydrogen, halogen, cyano, azido, nitro, —SCN, SF5, C1-C6-alkyl, C3-C8-cycloalkyl, C2-C6-alkenyl, C2-C6-alkynyl, wherein the carbon atoms of the aforementioned aliphatic and cyclo-aliphatic radicals may optionally be substituted with one or more R6, which are independently selected from one another;
• Si(R11)2R12, OR7, —OS(O)nR7, S(O)nR7, NR9aR9b, N(R9a)C(═O)R6, C(═O)R6, —C(═O)OR7, C(═NR8)R6, C(═S)R6,
• phenyl, optionally substituted with one or more substituents independently selected from R10, which are selected independently from one another;
• and
• a 3-, 4-, 5-, 6- or 7-membered saturated, partly saturated or unsaturated aromatic heterocyclic ring comprising 1, 2 or 3 heteroatoms selected from the group consisting of oxygen, nitrogen and sulfur, optionally substituted with k substituents R10, independently selected from one another, and wherein the nitrogen and/or the sulfur atom(s) of the heterocyclic ring may optionally be oxidized,
• or,
• when p is 2 or more and two of R4 are adjacent,
• the two adjacent R4 may form a bridge selected from the group consisting of CH2CH2CH2CH2, CH═CH—CH═CH, N═CH—CH═CH, CH═N—CH═CH, N═CH—N═CH, OCH2CH2CH2, OCH═CHCH2, CH2OCH2CH2, OCH2CH2O, OCH2OCH2, CH2CH2CH2, CH═CHCH2, CH2CH2O, CH═CHO, CH2OCH2, CH2C(═O)O, C(═O)OCH2, O(CH2)O, SCH2CH2CH2, SCH═CHCH2, CH2SCH2CH2, SCH2CH2S, SCH2SCH2, CH2CH2S, CH═CHS, CH2SCH2, CH2C(═S)S, C(═S)SCH2, S(CH2)S, CH2CH2NR9a, CH2CH═N, OCH═N, SCH═N, and CH═CH—NR9a, wherein the carbon atoms of the bridge may optionally be substituted with one or two substituents selected from the group consisting of ═O, OH, CH3, OCH3, halogen, halomethyl or halomethoxy.