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US 8,999,714 B2Granted
Mitochondrial enhancement of cells
AssigneeThe Invention Science Fund I, LLC
InventorsRoderick A. Hyde, Lowell L. Wood, Jr.
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Abstract
Certain embodiments disclosed herein include, but are not limited to, at least one of compositions, methods, devices, systems, kits, or products regarding rejuvenation or preservation of stem cells. Certain embodiments disclosed herein include, but are not limited to, methods of modifying stem cells, or methods of administering modified stem cells to at least one biological tissue.
Claims9
A method of modifying a eukaryotic cell, comprising:
- selecting a eukaryotic cell for modification;
- and
- extracting mitochondria or mitochondrial DNA from a maternally genetically related platelet and modifying the selected eukaryotic cell by transferring the extracted mitochondria or mitochondrial DNA to the selected eukaryotic cell
- wherein the mitochondrial DNA of the maternally genetically related cell includes fewer mutations than the endogenous mitochondrial DNA of the selected eukaryotic cell, and the selected eukaryotic cell is from a subject that is chronologically older than the subject from which the mitochondrial DNA was extracted.
1 more element
Dependencies are inferred from the claim text.