Polysaccharide-protein binding model and nano-fibril formation of a starch binding domain
AssigneeNational Tsing Hua University
InventorsMargaret Dah-Tsyr Chang, Yuh-Ju Sun, Ping-Chiang Lyu, Shu-Chuan Lin, Wei-I Chou
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Abstract
A polysaccharide-protein binding model of SBD, and a fibril-forming 14-residue peptide consisting of X1NNNX2X3NYQX4X5X6X7X8, wherein the X1 and X8 mean a pair of opposite charged amino acid residues, and the X2, X3, X4, X5, X6, or X7 means an amino acid residue is described. A mixture for diminishing a polysaccharide, comprising at least two starch binding domains (SBDs) and a polysaccharide in a helix form is also presented. A method of providing an oligosaccharide, and a method of producing an amyloid-like fibril and use thereof are further described.
Claims4
A mixture for diminishing an amylose or amylopectin aggregate, comprising at least two RoGACBM21 (family 21 carbohydrate binding module from Rhizopus oryzae glucoamylase) and an amylose or amylopectin aggregate in a helix form.
Dependencies are inferred from the claim text.