Oil-in-oil emulsified polymeric implants containing a hypotensive lipid and related methods
AssigneeAllergan, Inc.
InventorsPatrick M. Hughes, Michele Boix, Christian Sarrazin, Marina Do
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AssigneeAllergan, Inc.
InventorsPatrick M. Hughes, Michele Boix, Christian Sarrazin, Marina Do
Estimating the term…
Biocompatible intraocular implants, such as microparticles, include a prostamide component and a biodegradable polymer that is effective in facilitating release of the prostamide component into an eye for an extended period of time. The prostamide component may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers. Or, the prostamide component may be encapsulated by the polymeric component. The present implants include oil-in-oil emulsified implants or microparticles. Methods of producing the present implants are also described. The implants may be placed in eye to treat or reduce a at least one symptom of an ocular condition, such as glaucoma.
A population of microparticles comprising a polymeric component encapsulating a prostamide component in the form of oil-in-oil emulsified microparticles having a maximum particle diameter less than about 200 μm, wherein the prostamide component comprises bimatoprost, a combination of bimatoprost and latanoprost, or a combination of bimatoprost and travoprost.
Dependencies are inferred from the claim text.