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US 8,999,394 B2Granted
Pancreatine pellets and method of producing same
OwnerThomas Moest, Manfred Kurfürst +1inventors
InventorsThomas Moest, Manfred Kurfürst, Walter Doleschal
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Abstract
In order to prevent impairment of the pharmacological effect of pancreatine through added auxiliary substances or binding agents a pancreatine pellet consists exclusively of pancreatine.
Claims6
A pancreatine pellet comprising a core consisting of pancreatine, and a coating comprising pancreatine,
- which coating has a first inner layer and a second outer layer,
- wherein the first inner layer surrounds the core and comprises auxiliary substances and binding agents, in an amount between 5-30% by weight of the pancreatine pellet,
- wherein the auxiliary substances, binding agents and pancreatine of the coating are homogeneously dispersed in the first inner layer,
- and wherein the second outer layer comprises a material that is resistant to gastric juices, in an amount between 10-30% by weight of the pancreatine pellet,
- and wherein the pancreatine pellet has a drop-like or spherical shape.
2 more elements
A pharmaceutical composition, comprising a pharmacologically active quantity of pancreatine pellets which comprise a core consisting of pancreatine, which core contains no auxiliary substances and binding agents, and a coating comprising pancreatine,
- which coating has a first inner layer and a second outer layer,
- wherein the first inner layer surrounds the core and comprises auxiliary substances and binding agents, in an amount between 5-30% by weight of the pancreatine pellet,
- wherein the auxiliary substances, binding agents and pancreatine of the coating are homogeneously dispersed in the first inner layer,
- and wherein the second outer layer comprises a material that is resistant to gastric juices, in an amount between 10-30% by weight of the pancreatine pellet,
- and wherein the pancreatine pellet has a drop-like or spherical shape.
2 more elements
Dependencies are inferred from the claim text.