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OwnerMuneera Mohamed Shafee, Ruckmani Kandasamy +3inventors
InventorsMuneera Mohamed Shafee, Ruckmani Kandasamy, Thusleem Omar Abdulgani, Saleem Zainuddin Shaikh, Anand Vasantharao Kondaguli
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The present invention provides a method of creating a macro environment in the stomach for immediate release of acid labile compounds stable at alkaline or near alkaline pH comprising the step of administering a composition comprising acid labile compound stable at alkaline or near alkaline pH together with a water soluble buffer, a water insoluble buffer, a disintegrant and pharmaceutically acceptable excipients. The present invention also provides a pharmaceutical composition of a multi component system in which one component essentially contains an acid labile drug and the other component comprises a fast releasing buffer composition along with pharmaceutically acceptable excipients for oral administration and ingestion by a subject, and process for preparing the same.
A method of creating a macro environment having a pH in the range of 5 to 10 in the stomach for immediate release of an active ingredient comprising the step of administering a composition comprising first and second components;
The method of 1, wherein the acid labile compound is a prazole.
A pharmaceutical composition for immediate release of acid labile compounds comprising first and second components, the first component comprising an active ingredient selected from an acid labile compound stable at pH between 5 to 10 or an alkali soluble compound, in a core, further comprising a stabilizing agent, lubricant, and other pharmaceutically acceptable excipients;
Dependencies are inferred from the claim text.