Self-emulsifying pharmaceutical compositions of rhein or diacerein
AssigneeWockhardt Limited
InventorsPremchand Nakhat, Prashant Mandaogade, Girish Kumar Jain, Munish Talwar
Life of this patent
Estimating the term…
Abstract
The invention relates to self emulsifying drug delivery system based compositions of rhein or diacerein, or salts or esters or prodrugs thereof which are bioequivalent to a 50 mg diacerein formulation marketed under the trade name Art 50®. The compositions exhibit no variability in fed and fasted state conditions. The compositions also result in significant reduction in side effects such as, soft stools effects as compared to Art 50®. The invention also relates to methods for preparing such compositions.
Claims7
A pharmaceutical composition comprising from about 10-90% w/w of diacerein, about 1-70% w/w of Labrafil, about 10-90% w/w of polyoxyethylene glycerol esters of fatty acid, about 5-70% w/w of PEG-40 hydrogenated castor oil, about 5-60% w/w of Lauroyl polyoxylglycerides and about 2-50% w/w of HPC.
Dependencies are inferred from the claim text.