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US 8,999,327 B2Granted
Antibodies against human CSF-1R and uses thereof
AssigneeHoffman-La Roche Inc.
InventorsNikolaos Dimoudis, Georg Fertig, Alexander Fidler, Klaus Kaluza, Marlene Pickl, Carola Ries, Stefan Seeber, Martin Lanzendoerfer
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Abstract
The present invention relates to antibodies against human CSF-1R (anti-CSF-1R antibody), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
Claims10
An isolated antibody binding to human CSF-1R, wherein
- the heavy chain variable domain comprises SEQ ID NO:39 and the light chain variable domain comprises SEQ ID NO:40.
An isolated antibody binding to human CSF-1R, wherein
- the heavy chain variable domain comprises a CDR3 region comprising SEQ ID NO:
- 33, a CDR2 region comprising SEQ ID NO:
- 34, and a CDR1 region comprising SEQ ID NO:
- 35, and the light chain variable domain comprises a CDR3 region comprising SEQ ID NO:
- 36, a CDR2 region comprising SEQ ID NO:
- 37, and a CDR1 region comprising SEQ ID NO:
- 38.
4 more elements
Dependencies are inferred from the claim text.