Oral vaccination of fish with live attenuated Edwardsiella ictaluri vaccines
AssigneeMississippi State University
InventorsDavid J. Wise, Terrence Greenway, Todd Byars
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Abstract
The present invention is directed to a novel live attenuated isolate and sub-isolets thereof of a strain of the pathogen Edwardsiella ictaluri for protecting fish from ESC infection or disease, a vaccine composition comprising the isolet, a method of oral delivery of the vaccine and any vaccine, and an apparatus designed to effectively mix the vaccine with fish feed and deliver the vaccine to fish.
Claims23
A live attenuated cultured isolate of a strain of the gram negative enteric bacterium pathogen Edwardsiella ictaluri that is resistant to rifamycin and that protects fish from virulent isolate E. ictaluri strains and infection, wherein the live attenuated cultured isolate of a strain of E. ictaluri is selected from at least one or more of the sub-isolates of the attenuated culture S97-773-340X.
Dependencies are inferred from the claim text.