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US 8,999,294 B2Granted
Nanoparticles for use in tumor diagnosis and therapy
AssigneeBoard of Regents, The University of Texas System
InventorsWei Chen, Yuebin Li
Life of this patent
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Abstract
The present invention relates to diagnostic and therapeutic nanoparticles. More particularly, the present invention relates to creating a copper (Cu)-based nanoparticle and a method for making the same. The Cu-based nanoparticles can further be incorporated with additional therapeutic or diagnostic compounds and used for the diagnosis and treatment of tumors.
Claims2
A method for the removal of cancer cells, the method comprising the steps of:
- (a) providing optically heatable nanoparticles having diameters of about 3 nm, wherein the optically heatable nanoparticles have the formula CuxSy (0<x<1, 0<y<1);
- (b) delivering the nanoparticles to target cancer cells;
- (c) optically heating the nanoparticles located at the target cancer cells for a period of time ranging from 3-5 minutes, whereby optically heating the nanoparticles results in thermal ablation of at least a portion of the target cancer cells;
- (d) increasing the temperature of the cancer cells;
- and (e) decreasing the viability of the cancer cells by at least 40%.
2 more elements
Dependencies are inferred from the claim text.