Methods for treating and diagnosing blinding eye diseases
AssigneeTranslatum Medicus Inc.
InventorShelley Romayne Boyd
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Abstract
This invention relates to, in part, methods and compositions that are useful for the diagnosis, treatment, or prevention of a blinding eye disease, including in the discovery of drugs that are efficacious against these diseases. Diseases include, for example, age related macular degeneration and reticular pseudodrusen disease, and the methods described herein include, for example, the method named delayed near infrared analysis (DNIRA).
Claims10
A method for reducing the rate of progression of dry age related macular degeneration (AMD), comprising intravitreally administering to a subject in need thereof an effective amount of a compound of Formula I:
- or a pharmaceutically acceptable salt thereof,
- wherein:
- each of R1 and R2 is independently H or a C1-C6 alkyl and
- R3 is H or a C1-C6 alkyl.
A method for reducing the rate of expansion of geographic atrophy in an eye of a subject afflicted with dry age related macular degeneration (AMD), comprising ophthalmically administering to the subject an effective amount of a compound of Formula I:
- or a pharmaceutically acceptable salt thereof,
- wherein:
- each of R1 and R2 is independently H or a C1-C6 alkyl, and
- R3 is H or a C1-C6 alkyl.
The method of 9, wherein the bindarit is formulated for sustained release.
Dependencies are inferred from the claim text.