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US 8,999,130 B2Granted
Field effect based nanosensor for biopolymer manipulation and detection
AssigneeInternational Business Machines Corporation
InventorsAjay K. Royyuru, Chao Wang
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Abstract
A mechanism is provided for manipulating a molecule. The molecule is driven into a nanochannel filed with electrically conductive fluid. A first vertical electric field is created inside the nanochannel to slow down the molecule and/or immobilize the molecule. The molecule is stretched into non-folded linear chains by the first vertical electric field and a horizontal electric field. Monomers of the molecule are sequentially read.
Claims14
A method for manipulating a molecule, the method comprising:
- driving the molecule into a nanochannel filed with electrically conductive fluid;
- creating, by a first pair of trapping electrodes, a first vertical electric field inside the nanochannel to at least one of:
- slow down the molecule and immobilize the molecule;
- wherein the first pair of trapping electrodes are positioned to the nanochannel and comprise a first top electrode and a first bottom electrode;
- wherein a top high-k dielectric material separates the nanochannel from the first top electrode, such that the first top electrode does not form the nanochannel;
- and
- wherein a bottom high-k dielectric material separates the nanochannel from the first bottom electrode, such that the first bottom electrode does not form the nanochannel;
- stretching the molecule into non-folded linear chains by the first vertical electric field and a horizontal electric field;
- and
- sequentially reading monomers of the molecule.
7 more elements
Dependencies are inferred from the claim text.