Manufacturing method for medical equipment for reducing platelet adhesion on a surface in contact with blood
AssigneeThoratec Corporation
InventorsTakehisa Mori, Atsushi Okawa, Takeshi Tsubouchi, Kensuke Uemura
Life of this patent
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Abstract
A manufacturing method for medical equipment involves electron beam irradiating a titanium or titanium alloy substrate surface that has at least been machined, whereby platelet adhesion of the surface to be contacted by blood is reduced. The manufacturing method for medical equipment can also use a specific pre-processing method and an electron beam irradiation method to reduce the platelet adhesion of the surface which is to be contacted with blood, to suppress the formation of minute depressions (craters) in the surface, which can occur due to the irradiation by an electron beam.
Claims19
A method of manufacturing a medical device possessing a medical device configuration and configured to contact blood, the method comprising:
- cutting the medical device from a base material so that the medical device possesses a medical device configuration, the base material being either titanium or titanium alloy, the medical device produced by the cutting possessing an outer surface, and the cutting of the base material reducing a size of crystal grains of the titanium or titanium alloy;
- subjecting the medical device produced by cutting the base material to heat-treatment to thermally expand the crystal grains of the titanium or titanium alloy that were reduced in size by the cutting;
- and
- subjecting the outer surface of the medical device which was subjected to the heat-treatment to electron beam irradiation to reduce platelet adhesion to the outer surface of the medical device when the outer surface of the medical device contacts the blood.
A method of manufacturing a medical device possessing a medical device configuration and configured to contact blood, the method comprising:
- cutting the medical device possessing the configuration from a titanium base material or titanium alloy base material to produce a medical device made of the titanium or the titanium alloy base material and possessing the medical device configuration, the medical device produced by the cutting possessing an outer surface;
- and
- electron beam irradiating the outer surface of the medical device possessing the medical device configuration to decrease surface roughness and thus reduce platelet adhesion to the outer surface of the medical device when the outer surface of the medical device contacts the blood.
A method of manufacturing a medical device comprising subjecting a surface of a titanium base material or titanium alloy base material which has previously undergone at least a cutting process to electron beam irradiation to reduce platelet adhesion of the surface when the surface comes into contact with blood.
Dependencies are inferred from the claim text.