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US 8,993,545 B2Granted
Carbonate prodrugs and methods of using the same
AssigneeAcorda Therapeutics, Inc.
InventorsNaweed Muhammad, Keith R. Bley
Life of this patent
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Abstract
The present invention provides carbonate prodrugs which comprise a carbonic phosphoric anhydride prodrug moiety attached to the hydroxyl or carboxyl group of a parent drug moiety. The prodrugs may provide improved physicochemical properties over the parent drug. Also provided are methods of treating a disease or condition that is responsive to the parent drug using the carbonate prodrugs, as well as kits and unit dosages.
Claims12
A method of treating a disease or condition that is responsive to acetaminophen, comprising administering to an individual an effective amount of the prodrug:
- or a pharmaceutically acceptable salt thereof or solvate of the foregoing.
Dependencies are inferred from the claim text.