Method for inducing differentiation of dental pulp cells into odontoblasts
AssigneeNational University Corporation Okayama University
InventorsTakashi Yamashiro, Hiroshi Kurosaka, Noriaki Kawanabe
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Abstract
Provided is an efficient method of inducing differentiation of a pulp cell into an odontoblast. Also provided is an agent for inducing differentiation capable of inducing differentiation into an odontoblast efficiently. The method of inducing differentiation of a pulp cell into an odontoblast includes using a substance capable of activating a Wnt signaling pathway. Further, the agent for inducing differentiation includes a substance capable of activating a Wnt signaling pathway. Specifically, the substance capable of activating a Wnt signaling pathway is any one selected from sodium perchlorate, sodium perchlorate, lithium chloride, Norrin, and R-Spondin2.
Claims5
A method of inducing differentiation of a pulp (MEDP) cell into an odontoblast comprising administering to said cell an effective amount of a substance under conditions sufficient to cause differentiation of said cell into an odontoblast, wherein said substance is selected from the group consisting of sodium chlorate, sodium perchlorate, Norrin, R-Spondin2, or a combination thereof.
Dependencies are inferred from the claim text.