Metal-citrate transporter antigen from Streptomyces coelicolor and uses thereof
AssigneeSyracuse University
InventorsRobert P. Doyle, Joshua J. Lensbouer
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Abstract
The present invention relates to an isolated antigen from Streptomyces coelicolor that is useful for developing, inter alia, vaccines against pathogenic bacteria of humans and animals. The present invention also relates to vaccines and antibodies developed using the isolated antigen. The present invention also relates to methods of using the antigen, vaccines, and antibodies of the present invention to detect, treat, and prevent infection and diseases associated with pathogenic bacteria.
Claims7
A single chain monoclonal antibody that specifically binds to a solvent exposed region of a metal-citrate transporter from Streptomyces coelicolor, wherein said antibody is suitable for oral, parenteral, intravenous, subcutaneous, intranasal, or aerosolized administration in a human or animal.
A pharmaceutical composition comprising:
- a single chain monoclonal antibody that specifically binds to a solvent exposed region of a metal-citrate transporter from Streptomyces coelicolor, wherein said antibody is suitable for oral, parenteral, intravenous, subcutaneous, intranasal, or aerosolized administration in a human or animal;
- and
- a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.