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US 8,987,498 B2Granted
Enantiomerically pure amines
AssigneeNabriva Therapeutics AG
InventorsRosemarie Riedl, Werner Heilmayer, Lee Spence, Atchyuta Rama Chandra Murty Bulusu
Life of this patent
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Abstract
A compound of formula wherein PROT is an amine protecting group and PROT′ is hydrogen; or PROT and PROT′ together with the nitrogen atom to which they are attached form a heterocyclic ring as an amine protecting group, and PROT″ is a thiol protecting group, processes for its production, intermediates in their production and production of intermediates in stereoisomerically pure form, and their use for the production of pharmaceutically active compounds.
Claims19
A compound of formula I
- wherein
- PROT is selected from
- ethoxycarbonyl,
- 2,2,2-trifluoroacetyl, and
- PROT′ is hydrogen;
- or
- PROT and PROT′ together with the nitrogen atom to which they are attached form a heterocyclic ring as an amine protecting group, and
- PROT″ is a thiol protecting group.
5 more elements
Dependencies are inferred from the claim text.