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US 8,986,726 B2Granted
Biocompatible polyacrylate compositions for medical applications
AssigneeAbbott Cardiovascular Systems Inc.
InventorSyed F. A. Hossainy
Life of this patent
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Abstract
A composition comprising a structural component comprising linear acrylic homopolymers or linear acrylic copolymers and a biobeneficial component comprising copolymers having an acrylate moiety and a biobeneficial moiety is disclosed. A medical article comprising the composition in the coating thereof and a method of fabricating the medical article are also disclosed.
Claims26
A composition comprising:
- (a) a biologically compatible structural component comprising a linear acrylic homopolymer or a linear acrylic copolymer;
- and
- (b) a biobeneficial component comprising a copolymer having an acrylate moiety and a biobeneficial moiety;
- wherein the copolymer composing the biobeneficial component has the formula:
- wherein
- (a) m1, n1, p1, r1, m2, n2, p2, and r2 are all integers;
- (b) m1≧0, n1>0, p1≧0, r1>0;
- m2≧0, n2>0, p2≧0, r2>0;
- and
- (c)
- (i) if m1=0, then p1>0;
- (ii) if p1=0, then m1>0;
- and
- (iii) if m2=0, then p2 >0;
- and
- (iv) if p2=0, then m2>0;
- and
- (v) r1 and r2 are the same or different;
- (vi) m1 and m2 are the same or different;
- (vii) n1 and n2 are the same or different;
- and
- (viii) p1 and p2 are the same or different;
- (d) X is hydrogen or methyl group;
- (e) each of R, R1 and R2, independently, is methyl, ethyl, n-propyl, iso-propyl, n-butyl, sec-butyl, iso-butyl, tert-butyl, lauryl, or 2-hydroxyethyl;
- and
- (f) Q is a fragment providing the copolymer with biobeneficial or bioactive properties.
23 more elements
Dependencies are inferred from the claim text.