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US 8,986,724 B2Granted
Nitric oxide generating medical devices
AssigneeAdvanced Cardiovascular Systems, Inc.
InventorsThierry Glauser, Stephen D. Pacetti, Paul M. Consigny
Life of this patent
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Abstract
Medical devices having a catalyst capable of catalyzing the generation of nitric oxide in vivo and methods of treating a vascular condition using the devices are provided.
Claims18
A medical device comprising a metal complex comprising a metal and at least one ligand, at least one of the ligands being a bipyridine ligand;
- wherein the metal complex attaches to a surface of the medical device or a coating on the medical device via a spacer, wherein the spacer is a short chain alkyl group, phenyl group, aryl group, or poly(ethylene glycol), and
- wherein the metal complex catalyzes the in-vivo generation of nitric oxide.
Dependencies are inferred from the claim text.