Newcastle disease virus vectored herpesvirus vaccines
AssigneeMerial Limited
InventorsMichel Bublot, Frederic Reynard, Herve Poulet, Frederic Raymond David
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Abstract
The present invention encompasses recombinant Newcastle Disease Virus-Herpesvirus vaccines or compositions. The invention encompasses recombinant NDV vectors encoding and expressing herpesvirus pathogen, antigens, proteins, epitopes or immunogens. Such vaccines or compositions can be used to protect animals against disease.
Claims33
A composition comprising a first and a second recombinant Newcastle Disease Virus (NDV) vector, wherein the first recombinant NDV vector comprises a heterologous polynucleotide encoding a feline Herpesvirus glycoprotein B (gB) antigen or polypeptide, and the second recombinant NDV vector comprises a heterologous polynucleotide encoding a feline Herpesvirus glycoprotein D (gD) antigen or polypeptide, and wherein the first and/or the second NDV comprises a polynucleotide having the sequence as set forth in SEQ ID NO:27.
A recombinant NDV vector comprising a heterologous polynucleotide encoding a feline Herpesvirus gB antigen, and/or a heterologous polynucleotide encoding a feline Herpesvirus gD antigen, wherein the NDV comprises a polynucleotide having the sequence as set forth in SEQ ID NO:27.
The composition 1, wherein the gB antigen has at least 90% sequence identity to SEQ ID NO:1.
Dependencies are inferred from the claim text.