Antibodies and processes for preparing the same
AssigneeTaiga Biotechnologies, Inc.
InventorsYosef Refaeli, Brian Curtis Turner
Life of this patent
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Abstract
Provided herein are various processes for the improved production of antibody producing organisms, antibody producing tissues, antibody producing cells and antibodies. In certain embodiments, provided herein are methods for rapidly producing antibody producing organisms, tissues, cells and antibodies derived from humans, organisms, plants or cells that are genetically altered to over-express certain proteins.
Claims23
A method for generating a B-cell that expresses antibodies specific for a selected antigen comprising:
- contacting an antibody expressing B-cell with (i) the selected antigen and (ii) an exogenous fusion peptide, wherein the fusion peptide comprises (a) a peptide transduction domain, and (b) Myc, under conditions wherein the presence of the fusion peptide and the selected antigen promotes proliferation and survival of the B-cell that expresses antibodies specific for the selected antigen.
A method for culturing a B-cell that expresses antibodies specific for a selected antigen ex vivo comprising:
- contacting the B-cell that expresses antibodies with (i) a selected antigen and (ii) an exogenous fusion peptide, wherein the fusion peptide comprises (a) peptide transduction domain, and (b) Myc, under conditions wherein the presence of the fusion peptide and the selected antigen promotes proliferation and survival of the B-cell that expresses antibodies specific for the selected antigen ex vivo.
Dependencies are inferred from the claim text.