Loading patent…
AssigneeInhibrx, Inc.
InventorsJohn Timmer, Brendan Eckelman, Grant B. Guenther, Peter L. Nguy, Henry Chan, Quinn Deveraux
Estimating the term…
This invention relates to fusion proteins that include a whey acidic protein (WAP) domain-containing polypeptide and a second polypeptide. Additionally, the invention relates to fusion proteins that include a WAP domain-containing polypeptide, a second polypeptide, and a third polypeptide. The second and/or third polypeptides of the fusion proteins of the invention are an Fc polypeptide; an albumin polypeptide; a cytokine targeting polypeptide; or a serpin polypeptide. This invention also relates to methods of using such molecules in a variety of therapeutic and diagnostic indications, as well as methods of producing such molecules.
An isolated fusion protein comprising at least one human whey acidic protein (WAP) domain-containing polypeptide comprising a human secretory leukocyte proteinase inhibitor (SLPI) polypeptide comprising the amino acid sequence of SEQ ID NO:
An isolated fusion protein comprising at least one human secretory leukocyte proteinase inhibitor (SLPI) polypeptide comprising the amino acid sequence of SEQ ID NO:
An isolated fusion protein comprising human at least one human Elafin polypeptide comprising the amino acid sequence of SEQ ID NO:
Dependencies are inferred from the claim text.